Lorstat 20 mg (Rosuvastatin Calcium)

Adult dose

The initial dose is 5 mg once daily, and if a greater reduction in LDL cholesterol is needed, the maintenance dose may be adjusted accordingly. The maintenance dose is typically 10 mg once daily, with most patients being managed at this dosage level. The maintenance dose should be appropriately adjusted, considering LDL cholesterol levels, treatment goals, and patient response, with the maximum dosage being 20 mg once daily, with increases made at intervals of 4 weeks or more.

Child dose

For pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17), the usual dosage range is 5 mg to 20 mg once daily. The dosage will be adjusted based on the individual patient's recommended treatment goals.

This medication should not be prescribed to certain patients. For example, it should not be used in patients who are allergic to this medication, have liver dysfunction, have muscle disorders, have severely impaired kidney function, are pregnant or breastfeeding, or are taking certain medications alongside this drug. Additionally, liver function and muscle condition should be monitored regularly while using this medication, and patients should inform their doctor immediately if they experience symptoms such as muscle pain, muscle weakness, or sudden fatigue. These symptoms, though rare, could signal serious side effects. Caution should be exercised when administering this medication to patients who consume large amounts of alcohol or have a history of liver disease. If the patient has conditions such as hypothyroidism or nephrotic syndrome, this condition must be treated before using this medication. Furthermore, this medication can interact with some other drugs; therefore, patients must inform their doctor or pharmacist if they are taking any other medications. There is an increased risk for muscle side effects when taken with certain antiviral agents, immunosuppressants, antibiotics, and some lipid-lowering drugs. Women of childbearing potential should employ adequate contraception before taking this medication and avoid its use during pregnancy. It is also advisable for nursing mothers to abstain from using this medication. In cases of overdose, there is no specific antidote; patients should seek medical attention immediately for appropriate treatment, and liver function and muscle enzyme levels should be monitored. Lastly, patients should be aware that this medication may cause dizziness or headache, and caution is needed when driving or operating machinery.

Serious side effects

• Hives, severe swelling (edema), chest tightness, difficulty breathing, profuse sweating, paleness, severe allergic reactions
• Severe rash accompanied by high fever, blisters, skin peeling, mucous membrane pain in the mouth/eyes, severe skin adverse reactions
• Shortness of breath or difficulty breathing, asthmatic attacks, respiratory irregularities with cough + fever
• Skin or eyes turning yellow (jaundice), profound lethargy, liver abnormalities (jaundice)
• Sudden and severe headaches,

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash and hives
• myalgia
• asthenia
• diarrhea

This medication should be stored in a tightly closed container to prevent exposure to air and moisture, and it is recommended to store it at room temperature between 1°C and 30°C. Storing it this way will help maintain the medication's effectiveness and prevent degradation.

Appearance

Pink, round film-coated tablet

Package unit

30 tablets/bottle