Medication info

Nafri Tablets (Nafronil Oxalate)

Prescription medicationTabletOralApproval withdrawn
Ingredient · strength
Nafronyl Oxalate›100mg / 1 tablet
Manufacturer / importer
Youngil Pharmaceutical Co., Ltd.
Appearance
White round film-coated tablets
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Approval withdrawn

MFDS item code 201400179 · Notified 2014.01.15

This product's status changed to Approval withdrawn on 2024.03.22. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Treatment of peripheral vascular disorders
Who takes it
Adults
Adult dose
Administer 100 mg of nafronyl oxalate orally 3 times daily.

Ingredients

Manufacturer
Youngil Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of peripheral vascular disorders

  • Peripheral vascular disorders
View approved original text

Peripheral vascular disorders are conditions that cause poor blood circulation in the hands and feet, leading to symptoms such as numbness, pain, and cold sensations. This medication improves the function of the peripheral vasculature, facilitating blood flow. Therefore, it helps relieve numbness and pain in the hands and feet, and is used to improve overall blood circulation.

How to take

Adult dose

Administer 100 mg of nafronyl oxalate orally 3 times daily.

Precautions

This medication should not be used in patients with acute myocardial infarction or in the early stages of bleeding injuries. Patients with orthostatic dysregulation or a history of allergic reactions to this medication should also not take it. It is contraindicated for patients with hyperoxaluria or recurrent calcium kidney stones, as well as those with acute heart failure or congestive heart failure. Patients with cardiac conduction defects, angina, severe hypotension, liver function issues, or those at risk of seizures should not be treated with this drug. Pregnant women, those who may become pregnant, and nursing mothers are advised not to use this medication. It should be used cautiously in patients with impaired kidney function or coronary artery disease. Neurogenic symptoms such as convulsions, anxiety, drowsiness, headaches, and dizziness may occur while taking this medication. Gastrointestinal issues such as loss of appetite, vomiting, and diarrhea may also happen. Allergic reactions such as hives or rashes should be monitored. Liver function anomalies may lead to hepatitis or jaundice, and there is a risk of developing kidney stones. Cardiovascular symptoms such as hypotension, arrhythmias, angina, syncope, and edema have also been reported. Blood sugar levels may increase, so individuals requiring blood sugar monitoring should exercise caution. This medication is not used for hypertension treatment and sufficient water should be consumed to prevent kidney stones. Taking this medication without beverage before sleep may lead to esophagitis; thus, it must be taken with water. If taken together with antihypertensives or antiarrhythmics, the effects may be enhanced, so consultation with a healthcare provider is necessary. Women who are pregnant or breastfeeding should avoid this medication. In case of overdose, cardiac rhythm may be suppressed, or seizures may occur, necessitating immediate medical attention. Treatment includes gastric lavage, administration of activated charcoal, and monitoring of cardiac and respiratory function; severe cases may require specialized treatment.

Side effects

  • Brain convulsions
  • sensory abnormalities
  • anxiety
  • drowsiness
  • insomnia
  • fatigue
  • headache
  • dizziness
  • loss of appetite
  • esophagitis
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  • vomiting
  • nausea
  • abdominal pain
  • diarrhea
  • urticaria
  • angioedema
  • rash
  • hepatitis
  • cholesterol jaundice
  • acute hepatic cell necrosis
  • increased liver enzymes
  • liver failure
  • urinary disorders
  • calcium oxalate kidney stones
  • low blood pressure
  • orthostatic dysregulation
  • arrhythmia
  • angina
  • syncope
  • peripheral edema
  • elevated blood sugar

Not everyone experiences these, and they can vary from person to person.

Storage

Store this medication in a tightly closed container that can block light, and keep it in a temperature range between 1°C and 30°C.

Appearance and packaging

Appearance

White round film-coated tablets

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.