Colostatin 20 mg (Rosuvastatin Calcium)

Adult dose

This medication is taken once daily at any time, regardless of meals. The initial dose is 5 mg once daily, which can be adjusted to the maintenance dose if necessary. The maintenance dose of 10 mg once daily is adequate for most patients, and dosage adjustments should be made based on LDL cholesterol levels and treatment goals approximately every four weeks. The maximum dose is 20 mg once daily.

Child dose

For pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17 years), the dosage is administered once daily at 5 mg to 20 mg. The dosage should be adjusted according to each patient's treatment goals.

This medication should not be used in certain patients. For example, it should not be administered to patients who have an allergy to any component of this medication, those with active liver disease, patients with muscle disorders, patients with significantly impaired kidney function, and women who are pregnant or breastfeeding. Additionally, high doses are prohibited in patients at high risk of muscle disorders. Since this medication contains lactose, it should not be used in patients with lactose intolerance. When using this medication, liver function and muscle status should be monitored periodically. Patients who consume large amounts of alcohol or have a history of liver disease need to be particularly cautious. If symptoms like muscle pain, weakness, or cramps occur, consult a physician immediately. This medication may interact with other drugs, so inform your physician of any other medications you are taking. In particular, the risk of muscle damage may increase when combined with certain antiviral drugs, immunosuppressants, or fibrate derivatives. Women of childbearing potential should use adequate contraception while taking this medication, and should discontinue it immediately if they become pregnant. It is also safest for breastfeeding women not to take this medication. In cases of overdose, there is no specific antidote, so seek medical attention immediately for appropriate treatment. This medication can rarely cause serious side effects such as severe skin reactions, liver damage, kidney issues, and muscle damage, so report any unusual symptoms to medical personnel immediately. Dizziness may occur while driving or operating machinery, so caution is advised. The blood concentration of this medication may be higher in Asians, so dosage adjustments may be necessary. Monitoring growth and development is required when administering this medication to children and adolescents.

Serious side effects

• Allergic reactions including urticaria and angioedema
• Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS)
• Severe skin adverse reactions
• Rhabdomyolysis, myopathy
• Severe allergic reactions
• Respiratory distress accompanied by coughing and fever
• Liver abnormalities (jaundice), hepatitis
• Severe muscle weakness, ophthalmoplegia
• Thrombocytopenia
• Acute renal failure, oliguria

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• myalgia
• asthenia
• hematuria

This medication may be sensitive to air or moisture, so it must be stored in a tightly closed container. It is important to maintain the storage temperature between 1 degrees Celsius and 30 degrees Celsius. Proper storage will ensure the safety and efficacy of the medication.

Appearance

Pink round film-coated tablet

Package unit

30 tablets/bottle