Jaypolmin Tablets 500mg (Metformin Hydrochloride)

Adult dose

Dosage should be determined based on individual drug effects and tolerance. Administer 500mg 2 to 3 times a day with meals. Gradually increase the dosage by 500mg weekly, with a maximum of 2550mg possible. Generally, doses up to 2000mg are split into 2 daily doses. If exceeding 2000mg, divide into 3 daily doses with meals. Fasting blood sugar measurements and HbA1c level assessments are essential at 3-month intervals.

Child dose

Can be used for children over 10 years old and adolescents in growth. The starting dose is 500mg once daily, taken during or after meals. Adjust dosage after measuring blood sugar levels one week later. The maximum daily dose is 2000mg.

This medication can cause severe lactic acidosis or hypoglycemia, so caution is required. Patients with moderate or greater kidney impairment, dehydration, serious infections, acute myocardial infarction, and other conditions that can affect kidney function should not use this medication. Patients with acute and unstable heart failure or those scheduled for examinations using radiographic iodine contrast media should avoid using this medication and must discontinue it for a period before and after the examination. It should not be administered to patients with hypersensitivity to this medication or to biguanide drugs, nor to patients with type 1 diabetes, diabetic ketoacidosis, severe infections, or trauma. This medication should be temporarily discontinued before and after surgery until kidney function has returned to normal. Caution is necessary for patients with malnutrition, starvation, liver impairment, severe pulmonary function impairment, or excessive alcohol consumption. This medication can cause lactic acidosis, a rare but potentially fatal side effect, so if symptoms such as fatigue, muscle pain, shortness of breath, or abdominal pain occur, immediate medical attention should be sought. Gastrointestinal symptoms (diarrhea, nausea, vomiting) can commonly occur during initial treatment but are usually temporary, so dose adjustments or taking the medication with meals may help. Since this medication is excreted via the kidneys, regular assessment of renal function is necessary, and it should be discontinued if kidney function deteriorates sharply. The blood sugar control effect may change when used in combination with other hypoglycemic agents or specific medications, so patients should inform the healthcare provider of any medications they are taking and closely monitor their blood sugar status. Consumption of alcohol may increase the risk of side effects associated with this medication, so excessive intake should be avoided. During pregnancy, the use of this medication should be done cautiously considering its effects on the fetus, and it should not be used if there is a risk of placental insufficiency or preeclampsia. In lactating individuals, since this medication is secreted in breast milk, careful consideration must be given to breastfeeding and the necessity of treatment. Older adults often experience decreased kidney function, so dose adjustments and regular kidney function monitoring are important. In case of overdose, there is a risk of lactic acidosis, and immediate medical assistance should be sought; if necessary, the medication can be removed via hemodialysis. This medication has the advantage of not causing weight gain, but regular monitoring of blood sugar and kidney function is essential during use. Store this medication out of reach of children and avoid transferring it to other containers.

Serious side effects

Lactic acidosis (including symptoms similar to severe allergic reactions, such as hives, severe swelling, shortness of breath), severe kidney impairment, acute myocardial infarction, sepsis, heart failure, acute renal failure, liver abnormalities (jaundice), severe neurological symptoms (headache, seizures, altered consciousness), severe swelling and urinary abnormalities, cardiopulmonary diseases due to hypoxia, severe lactic acidosis, and severe hypoglycemia

Mild side effects

Gastrointestinal symptoms (diarrhea, nausea, vomiting, abdominal distension, loss of appetite, dyspepsia, constipation, abdominal pain), sensory disturbances (unpleasant metallic taste), rash, anemia, leukopenia, thrombocytopenia, vitamin B12 deficiency, abnormal liver function, hypoglycemia

This medication should be stored in a tightly sealed container to prevent air or moisture from entering, and it is best kept at room temperature between 1 to 30 degrees Celsius. This helps maintain its effectiveness over time.

Appearance

White, round film-coated tablet

Package unit

30 tablets/bottle, 500 tablets/bottle