Rabeprazole Sodium Tablet 20mg

Adult dose

Gastric ulcer, duodenal ulcer: 10 mg orally once daily, with a possible increase to 20 mg once daily depending on symptoms. Administer for 8 weeks for gastric ulcers and 6 weeks for duodenal ulcers. Erosive or ulcerative gastroesophageal reflux disease: administer 10 mg or 20 mg once daily for 4 to 8 weeks. If symptoms do not resolve after 8 weeks of treatment, an additional 10 mg or 20 mg can be administered twice daily for another 8 weeks.

This medication should not be administered to certain patients. For example, those who have allergies to this drug or its components or who have had hypersensitivity reactions to benzimidazoles should not use it. Additionally, patients with allergies to antibiotics such as amoxicillin or clarithromycin during Helicobacter pylori eradication therapy, and those taking certain heart-related medications (terfenadine, cisapride, pimozide, astemizole) should also avoid using this medication. Women who are pregnant or breastfeeding should not take this medication, and patients taking specific drugs such as atazanavir or rilpivirine should avoid combining them with this medication. Caution is also needed for patients with impaired liver function or the elderly, as well as for those with a history of drug hypersensitivity or allergies to color additives included in this medication. Allergic reactions, such as skin rash, itching, or hives, may occur, so discontinuation should be immediate if these symptoms appear. Various side effects may occur, including blood abnormalities, liver function issues, heart problems, gastrointestinal symptoms, neurological issues, respiratory problems, muscle and joint pain, skin disorders, visual or auditory disturbances, and urinary tract problems, so regular check-ups during treatment are recommended. Particularly, if liver function abnormalities or severe allergic reactions arise, immediate cessation of medication and appropriate measures should be taken. Long-term use of this medication may increase the risk of osteoporosis and fractures, so regular checks of condition are necessary for long-term administration exceeding one year. Moreover, prolonged use may lead to hypomagnesemia, necessitating periodic checks of magnesium levels and supplementation if required. This medication significantly suppresses gastric acid secretion, which may slightly increase the risk of bacterial infections in the stomach; thus, healthcare consultation is necessary if diarrhea persists. Caution is needed when driving or operating machinery as drowsiness may occur. This medication may also interact with other drugs; particularly, consultation with a professional is required when used in combination with warfarin, methotrexate, atazanavir, or rilpivirine. Pregnant or breastfeeding women should not use this medication, and the elderly may experience more pronounced side effects due to reduced liver function. Safety in children has not been established, and it is advisable not to use it in pediatric patients. This medication should be taken whole without chewing or crushing, and it should be kept out of reach of children and not transferred to another container. If any adverse symptoms occur during treatment, it is important to immediately consult a healthcare provider or pharmacist for appropriate measures.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, fulminant hepatitis, liver dysfunction, jaundice, severe allergic reaction, severe skin abnormal reaction, toxic epidermal necrolysis (Lyell syndrome), skin and mucosal syndrome (Stevens-Johnson syndrome), breathing difficulties, asthma attack, liver issues (jaundice), sudden and very severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, noticeable changes in urination

Mild side effects

• Occasionally rash
• hives
• itching
• red blood cell decrease
• white blood cell decrease
• white blood cell increase
• eosinophilia
• neutrophilia
• lymphocytopenia
• anemia

This medication must be stored in a tightly sealed container to avoid exposure to air or moisture. It is advisable to maintain storage temperatures between 1 and 30 degrees Celsius at room temperature to preserve the effectiveness and safety of the medication.

Appearance

Light yellow round enteric-coated tablet

Package unit

28 tablets (14 tablets/AluAlu packaging x2)