Stodin Tablet 10 mg (Rafutidine)

Adult dose

1. Short-term treatment of gastric ulcers: The usual dose is 10mg of lafutidine per dose, administered orally twice daily, in the morning and at bedtime. In clinical trials of up to 8 weeks, most ulcers healed within 8 weeks, although healing time may occasionally vary from patient to patient. 2. Short-term treatment of duodenal ulcers: The usual dose is 10mg of lafutidine per dose, administered orally twice daily, in the morning and at bedtime. In clinical trials of up to 6 weeks, most ulcers healed within 6 weeks, although healing time may occasionally vary from patient to patient. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis: The usual dose is 10mg of lafutidine once daily, administered orally at bedtime. In clinical trials of up to 2 weeks, most lesions healed within 2 weeks, although healing time may occasionally vary from patient to patient. 4. Combination therapy with antibiotics for patients with peptic ulcers infected with Helicobacter pylori: Administer lafutidine 20mg, clarithromycin 500mg, and amoxicillin 1000mg twice daily for 7 or 14 days. 5. Premedication before anesthesia: The usual dose is 10mg of lafutidine per dose, administered orally twice (at bedtime the day before surgery and 2 hours before anesthesia on the day of surgery). 6. Treatment of reflux esophagitis: Administer 10mg of lafutidine per dose orally twice daily.

This drug should not be used by patients who are allergic to any of its components. Additionally, this medication contains lactose, and it is advisable for patients with insufficient lactose-decomposing ability or lactose intolerance to avoid taking it. Patients with a history of drug allergies, those with liver or kidney problems, patients undergoing dialysis, and elderly patients should exercise greater caution when using this medication. This drug can cause severe allergic reactions or symptoms such as anaphylaxis; therefore, if you experience paleness in the face, low blood pressure, or difficulty breathing after taking it, immediately stop taking the medication and consult a healthcare professional. Liver function may worsen, so if liver function test results deteriorate, discontinue the medication and receive appropriate treatment. There may be a reduction in blood cell counts, such as agranulocytosis or thrombocytopenia, so immediate consultation with a doctor is advised if symptoms like sore throat, fatigue, or fever occur. Rarely, problems related to the heart or nervous system may arise, so it is essential to inform healthcare professionals quickly if unusual symptoms present themselves. In clinical trials and post-marketing surveys, side effects such as gastrointestinal symptoms (constipation, diarrhea, nausea, etc.), headache, drowsiness, dizziness, skin rash, etc., have been reported. Especially in cases where malignant tumors, such as gastric cancer, are suspected, precise examination should be conducted before taking this medication, and it should be discontinued if diagnosed with a malignant tumor. If there is no therapeutic effect from this drug, it is necessary to switch to alternative treatment options, and regular blood tests and liver and kidney function tests should be conducted. Elderly patients should take care to adjust the dosage and administration interval as their bodily functions decline. Patients with reduced kidney function, particularly those on dialysis, may have increased drug concentrations in the blood and should start with a low dose and be monitored closely. Pregnant women or those of childbearing potential should take this medication only when the benefits outweigh the risks as determined by a doctor, and nursing mothers are advised against taking it as it may be excreted in breast milk. Safety for children has not been established, and its use is not recommended. This drug should be kept out of reach of children and stored in its original container; transferring to another container may risk misuse or deterioration in quality. While this drug showed no carcinogenicity in animal studies, changes in gastric endocrine cells were observed at very high doses. Toxicity studies related to reproduction and development showed some side effects at high doses, but fetal malformations or developmental abnormalities were not observed.

• Shock
• symptoms of anaphylaxis
• facial pallor
• hypotension
• generalized pruritus
• dyspnea
• liver function impairment
• jaundice
• agranulocytosis
• pharyngalgia

This medication should be stored in a tightly sealed container to avoid exposure to air or moisture, and it is advisable to keep it at room temperature between 1 degree and 30 degrees Celsius. This storage method helps maintain the drug's effectiveness.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle, 500 tablets/bottle