Ibetapill (Irbesartan)

Adult dose

Essential hypertension adults: Administer 150 mg orally once daily of Irbesartan, which may be increased to 300 mg if the effect is insufficient. Generally, the blood pressure control effect for 24 hours is better when administering 150 mg compared to 75 mg once daily; however, in special cases (early treatment, hemodialysis patients, or those over 75 years of age), 75 mg may be considered.

This medication can cause serious harm to the fetus and newborn, especially during pregnancy, and should not be taken by pregnant women or women who may become pregnant. Patients with hypersensitivity to this medication, severe liver disease, hereditary angioedema, or specific genetic disorders should not receive it. Caution should be exercised when administering to elderly patients, those with hyperkalemia, and patients with liver disease, and blood pressure, kidney function, and electrolyte status should be monitored frequently. During treatment with this medication, mild side effects such as dizziness, fatigue, headache, and cough may occur; however, serious side effects may also rarely happen, so caution is needed. Serious adverse reactions such as angioedema, hyperkalemia, shock, renal failure, liver dysfunction, hypoglycemia, and rhabdomyolysis may occur, so immediate consultation with a healthcare professional is required if any unusual symptoms appear. For patients with impaired liver function, dose adjustment is necessary, and it is not administered to patients with severe liver disease. It is advisable not to take the medication for 24 hours prior to surgery, and there is a risk of hypotension in patients with reduced blood volume, so caution is needed. In patients with renal vascular hypertension or impaired kidney function, there is a risk of acute renal failure, so use should be avoided or administered carefully. This medication can be used in combination with other antihypertensives; however, it should be avoided in combination with potassium-sparing agents or potassium supplements as they may dangerously elevate potassium levels in the blood. When taken with lithium preparations, lithium levels may increase, resulting in toxicity, so blood levels should be monitored closely. Caution is needed when taken in combination with nonsteroidal anti-inflammatory drugs as they may reduce the antihypertensive effect or worsen kidney function. This medication may be excreted in breast milk, so breastfeeding women should avoid it or discontinue nursing. Safety in pediatric patients has not been established, and administration to children is not recommended. In cases of overdose, symptoms such as hypotension or arrhythmias may occur, necessitating immediate treatment. This medication should be stored out of reach of children and should not be transferred to another container for safety. Caution should be exercised while driving or operating machinery as dizziness or fatigue may be experienced.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, mucosal pain in the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, jaundice (yellowing of the skin or eyes), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination

Mild side effects

• Headache
• musculoskeletal pain
• dizziness
• fatigue
• diarrhea
• cough
• nausea/vomiting
• musculoskeletal trauma
• chest pain
• dyspepsia

This medication may be sensitive to air or moisture, so it must be stored in a tightly closed container. Additionally, it should be kept in a cool, dry place below 30 degrees Celsius to maintain effectiveness.

Appearance

White or almost white, oval-shaped tablets with both sides convex

Package unit

30 tablets/bottle, 100 tablets/bottle