Losartan Plus Tablet

Adult dose

The usual dose for adults is one tablet of losartan potassium 50 mg/hydrochlorothiazide 12.5 mg once daily. A dose exceeding losartan potassium 100 mg/hydrochlorothiazide 25 mg per day is not advisable. Patients whose blood pressure is not controlled with monotherapy of losartan or hydrochlorothiazide should start on a regimen of losartan potassium 50 mg/hydrochlorothiazide 12.5 mg once daily.

Child dose

There is no experience in using this medication in children and adolescents (under 18 years), so the losartan-hydrochlorothiazide combination should not be administered to this age group.

This medication can cause serious harm to the fetus if taken during pregnancy, especially in the second and third trimesters, so it must be discontinued immediately if pregnancy is confirmed. This medication should not be administered to patients who are allergic to its components, have severely impaired kidney function, anuria, severe liver disease, or are pregnant. Patients with extremely low blood pressure or kidney function issues, a history of liver disease, hyperuricemia or gout, elderly patients, etc., should use this medication with caution. This medication can affect blood electrolyte levels; therefore, potassium, sodium, and other levels should be checked regularly through blood tests, and immediate medical consultation is necessary if symptoms of electrolyte imbalance occur. The hydrochlorothiazide component can make the skin sensitive to sunlight, increasing the risk of skin cancer, so sunscreen should be used when exposed to sunlight, and any skin abnormalities should be reported immediately. Concurrent use of this medication with other antihypertensives or potassium supplements may lead to dangerously high potassium levels in the blood; therefore, potassium supplements or salt substitutes containing potassium should not be taken without consulting a doctor. Additionally, this medication can cause dizziness or drowsiness, so caution is needed when driving or operating machinery. There is insufficient experience in using this medication in children and adolescents, so it should not be administered to these populations. When storing this medication, keep it out of reach of children, and store it in the original container with the lid tightly closed to maintain quality.

Serious side effects

Hives, angioedema (may cause airway obstruction due to laryngeal/glottic swelling, swelling of the face/lips/pharynx/tongue), skin exfoliation, hemolysis, chest pain, facial swelling, fever, orthostatic hypotension, syncope, angina, arrhythmia (atrial fibrillation, sinus bradycardia, tachycardia, ventricular tachycardia, ventricular fibrillation), cerebrovascular accident, hypotension, myocardial infarction, secondary atrioventricular block, dyspnea, acute respiratory distress syndrome (ARDS), pulmonary edema, acute renal failure, liver

Mild side effects

Abdominal pain, edema/swelling, palpitations, back pain, dizziness, cough, sinusitis, upper respiratory infection, weakness/fatigue, diarrhea, nausea, headache, bronchitis, pharyngitis, angioedema (swelling of lips and eyelids and facial rash), chest pain, facial swelling, fever, orthostatic hypotension, syncope, angina, arrhythmia (atrial fibrillation, sinus bradycardia, tachycardia, ventricular tachycardia, ventricular fibrillation), hypotension, loss of appetite, constipation, toothache, dry mouth, dyspepsia, flatulence, stomach upset

This medication is sensitive to light and should be stored in a special container that avoids light. Additionally, store the medication at room temperature, between 1°C and 30°C, not too hot or too cold.

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle