Atorva 20 mg Tablet (Atorvastatin Calcium Trihydrate)

Adult dose

The recommended initial dose for hyperlipidemia is 10 mg of atorvastatin once daily; if more LDL cholesterol reduction is required, treatment may begin with 20 mg or 40 mg once daily. The medication is administered in a dosage range of 10 to 80 mg once daily. Dosing should be individualized based on treatment goals and responses, with lipid levels analyzed and dosages adjusted within 2 to 4 weeks. The treatment goal is to lower LDL cholesterol levels, so monitoring LDL cholesterol levels is recommended during treatment initiation and response evaluation. If LDL cholesterol levels cannot be monitored, total cholesterol levels should be used to evaluate treatment response. For patients with homozygous familial hypercholesterolemia, the dosing is 10 to 80 mg once daily, either in combination with other lipid-lowering therapies (e.g., LDL apheresis) or when such therapies are not possible. For pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17), the recommended initial dose of this medication is 10 mg once daily, with a maximum recommended dose of 20 mg once daily (no clinical data are available for doses higher than 20 mg in pediatric patient groups). The dose should be appropriately adjusted according to the recommended treatment goals for individual patients, with adjustments made at intervals of 4 weeks or more. ○ Patients with renal impairment: Renal conditions do not affect atorvastatin plasma concentrations or LDL cholesterol-lowering effects, so dose adjustment is not necessary. ○ Elderly patients: The effectiveness and safety for elderly patients (over 70 years old) are similar to those for the general adult patient population.

Child dose

For pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17), the recommended initial dose is 10 mg once daily, with a maximum dose of 20 mg once daily. The dosage should be adjusted at intervals of 4 weeks or more.

This medication should be discontinued immediately and a doctor consulted if any unusual muscle symptoms occur. Particular caution is needed if severe muscle pain, weakness, or cramps develop. This medication should not be used in patients with poor liver function or liver diseases, and regular liver function tests should be conducted. If symptoms of hepatitis or jaundice occur, medical personnel should be informed immediately. This medication should not be taken by women who are pregnant or may become pregnant, and by breastfeeding women. Women of childbearing potential should use appropriate contraception while taking this medication. This medication is not to be given to children under 10 years old or patients with specific genetic lactose intolerance disorders. As this medication has many drug interactions, it is crucial to consult with a doctor or pharmacist when taking it with certain antibiotics, antifungal agents, HIV treatments, and some antihypertensive medications. Elderly patients or those with reduced kidney function should be observed more closely due to an increased risk of muscle-related side effects while taking this medication. If symptoms such as muscle pain, weakness, or fever occur while taking this medication, the doctor should be informed immediately, and a blood test should be conducted. If significantly elevated serum creatine kinase levels are found, the medication should be discontinued. Taking this medication with grapefruit juice may increase blood concentration, increasing the risk of side effects, so it is advisable to avoid grapefruit juice. It is preferable to refrain from alcohol consumption during treatment and to undergo periodic liver function tests for liver health.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rashes accompanied by high fever, blisters, skin peeling, pain in oral or eye mucosa, shortness of breath or difficulty breathing, asthma attacks, breathing difficulties accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden severe headache, lightning headache, seizures, confusion, visual disturbances, paralysis, urination

Mild side effects

• Weakness
• fatigue
• chest pain
• peripheral edema
• fever
• nasopharyngitis
• hyperglycemia
• hypoglycemia
• weight gain
• loss of appetite

This medication may be sensitive to air or moisture, so it should be stored in a tightly closed container. The storage temperature should be maintained between 1 to 30 degrees Celsius room temperature. This will help maintain the medication's effectiveness for a longer period.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle