Medication info
Amlonin Tablets (Amlodipine Besylate)

Amlonin Tablets (Amlodipine Besylate)

Prescription medicationTablet경구
Ingredient · strength
Amlodipine Besylate›6.944mg / 1 tablet
Manufacturer / importer
(주)제뉴파마
Appearance
White octagonal tablet
Packaging
30 tablets/bottle, 500 tablets/bottle
Approval status
Active

MFDS item code 201309994 · Approved 2013.10.31 · Insurance code 698002140

Summary

Main use
Treatment of myocardial ischemia due to hypertension and coronary artery disease (stable and unstable angina) and reduction of hospitalization risk from angina.
Who takes it
Adults
Adult dose
Adults: Amlodipine 5 mg should be taken orally once a day, and may be increased up to a maximum of 10 mg per day based on the patient's response. Adjustments should be made appropriately based on age and symptoms.

Ingredients

Manufacturer
(주)제뉴파마

Efficacy & effects

Treatment of myocardial ischemia due to hypertension and coronary artery disease (stable and unstable angina) and reduction of hospitalization risk from angina.

  • Hypertension
  • fixed obstruction of the coronary artery
  • vascular spasms of the coronary vessels
  • vasoconstriction
  • myocardial ischemia
  • angina.
View approved original text

This medication is used for the treatment of myocardial ischemia caused by hypertension and stable and unstable angina. Additionally, in patients recently diagnosed with coronary artery disease through angiography who have no heart failure and an ejection fraction of more than 40%, it reduces the risk of hospitalization due to angina and lowers the risk associated with coronary artery revascularization. Therefore, it is used as a medication to assist in managing cardiovascular diseases.

How to take

Adult dose

Adults: Amlodipine 5 mg should be taken orally once a day, and may be increased up to a maximum of 10 mg per day based on the patient's response. Adjustments should be made appropriately based on age and symptoms.

Precautions

This medication should not be used in certain patients. For example, it is contraindicated for patients who have had allergies to this drug or similar classes of drugs, breastfeeding women, patients with severe liver dysfunction, patients with severe aortic stenosis, and those in a state of shock. Also, caution should be exercised when using it in patients with severe hypotension, those requiring dialysis due to renal failure, the elderly, and pregnant or potentially pregnant women. Various side effects may occur when using this medication. Common side effects include flushing, fatigue, swelling, palpitations, dizziness, headache, drowsiness, abdominal pain, and nausea. Rarely, symptoms such as low blood pressure, neurological abnormalities, erectile dysfunction, dry mouth, dyspepsia, liver function abnormalities, and skin rashes may occur, so consult a doctor if symptoms are severe or persistent. Patients with heart failure or liver dysfunction may be more sensitive to the effects and side effects of this medication, so they should use it with caution. This medication lowers blood pressure slowly and may not be suitable for patients with acute unstable angina. It is known not to significantly affect driving or operating machinery, but there may be instances of dizziness or drowsiness in some individuals, so caution is advised. This medication can interact with other medications. In particular, it is advisable to avoid taking it with grapefruit juice, as it may enhance the drug's effectiveness. Additionally, when used in combination with certain antibiotics or immunosuppressants, patients should follow their doctor's instructions, and it is always safest to consult with a healthcare professional when taking other medications. The safety of this medication during pregnancy or breastfeeding is not established, thus it should be used only when there are no alternative medications and it is absolutely necessary. It is recommended to discontinue breastfeeding while taking this medication. For children, effectiveness has only been confirmed in those aged 6 years and older; it should not be used in children under 6 years of age. For the elderly, the usual dosage is recommended, as their tolerance is similar to that of younger individuals. If an overdose occurs, severe hypotension or cardiac abnormalities may arise, so immediate medical attention is required for appropriate treatment. In cases of overdose, gastrointestinal lavage or activated charcoal may be helpful, and blood pressure and cardiac function should be closely monitored.

Side effects and when to seek care immediately

Serious side effects

  • Urticaria
  • toxic epidermal necrolysis
  • hepatitis
  • jaundice
  • severe swelling
  • severe allergic reactions
  • severe skin reactions
  • respiratory distress
  • serious neurological symptoms
  • severe edema
Show 5 more
  • urinary abnormalities
  • pulmonary edema
  • hypotension
  • shock
  • non-cardiogenic pulmonary edema.

Mild side effects

  • Flushing
  • fatigue
  • swelling
  • palpitations
  • dizziness
  • headache
  • drowsiness
  • abdominal pain
  • nausea
  • weakness
Show 26 more
  • lethargy
  • weight gain/loss
  • hypotension
  • vasculitis
  • tension increase
  • sensory loss
  • sensory disturbances
  • peripheral neuropathy
  • syncope
  • taste disturbances
  • tremors
  • extrapyramidal disorders
  • erectile dysfunction
  • gynecomastia
  • changes in bowel habits
  • dry mouth
  • dyspepsia
  • gingival hypertrophy
  • pancreatitis
  • vomiting
  • hyperglycemia
  • arthralgia
  • low back pain
  • muscle cramps
  • myalgia
  • leukopenia.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture, preferably at temperatures between 1 and 30 degrees Celsius. This way of storage helps maintain the medication's effectiveness and prevents deterioration.

Appearance and packaging

Appearance

White octagonal tablet

Package unit

30 tablets/bottle, 500 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.