Betafen Injection (Diclofenac β-Dimethylaminoethanol)

Adult administration

As Diclofenac beta-Dimethylaminoethanol, administer 90 mg deeply into one side of the upper gluteal area once per day. In severe cases, 90 mg can be administered twice daily, alternating the injections between both sides of the gluteus. After the initial treatment period, switch to oral tablets or suppositories. Adjust as appropriate according to age, disease, and symptoms.

This medication may cause gastrointestinal bleeding if taken by individuals who regularly consume more than three alcoholic drinks a day, so consultation with a doctor or pharmacist is essential. This drug may affect the cardiovascular system, increasing the risk of serious thrombotic events such as heart attack or stroke. Caution is particularly advised for those with cardiovascular disease or risk factors, and immediate consultation with medical personnel is necessary if symptoms occur. This medication may increase the risk of severe problems such as gastrointestinal bleeding, ulcers, and perforations, especially in the elderly. Immediate medical attention is required if gastrointestinal bleeding symptoms or pain occur during use. Severe allergic reactions can induce myocardial infarction, so if allergy symptoms or chest pain related to this medication appear, the drug should be discontinued immediately, and medical advice should be sought. For ampoule injections, caution is required as glass fragments may be mixed in when cutting the container, particularly for children and the elderly. Patients with a history of peptic ulcers, severe blood disorders, liver dysfunction, kidney dysfunction, hypertension, heart failure, hypersensitivity to this drug's components, allergic reactions to aspirin or other non-steroidal anti-inflammatory drugs, and patients undergoing coronary artery bypass graft surgery should not take this medication. Patients with a history of peptic ulcers, blood disorders, liver dysfunction, kidney dysfunction, hypertension, heart failure, hypersensitivity, bronchial asthma, ulcerative colitis, Crohn’s disease, esophageal pain disorders, the elderly, and children should use this medication with caution, and those sensitive to sodium bisulfite should be alert for potential allergic reactions. Rarely, this medication may cause various side effects, including shock, peptic ulcers, gastrointestinal bleeding, blood disorders, severe skin reactions, liver dysfunction, kidney dysfunction, asthma attacks, headaches, dizziness, and blood pressure changes. If these symptoms occur, the medication should be stopped immediately, and medical advice sought. This medication should be taken for the shortest duration at the minimum effective dose, and regular blood tests and liver and kidney function tests are necessary for long-term use. Particularly children with high fever, infants, the elderly, and those with wasting diseases should be closely monitored after administration. This medication should be avoided in combination with other non-steroidal anti-inflammatory drugs as the risk of side effects increases, and there may also be interactions with specific drugs, so consulting a physician is essential. During pregnancy, especially in the later stages, it may pose risks to the fetus, so use should be avoided, and during breastfeeding, it can be transmitted through milk potentially causing adverse reactions in the baby, so consideration for cessation of breastfeeding or the drug should be evaluated. Elderly and pediatric patients should be administered this medication at the minimum dose with caution, paying particular attention to adverse reactions.

Serious side effects

Hives, chest tightness, difficulty breathing, severe swelling (edema), rash, significantly reduced urine output, elevated blood pressure, severe allergic reactions, severe skin reactions (Stevens-Johnson syndrome, Lyell's syndrome), jaundice, liver abnormalities (hepatic dysfunction), acute renal failure, asthma attacks, shortness of breath or difficulty breathing, severe neurological symptoms (headache, seizures, confusion, visual disturbances, paralysis), severe swelling, elevated blood pressure

Mild side effects

• Loss of appetite
• nausea
• vomiting
• abdominal pain
• diarrhea
• stomatitis
• thirst
• constipation
• headache
• drowsiness

This medication is sensitive to light and should be stored in an airtight container that does not allow light in. It is best to maintain a storage temperature between 1 and 30 degrees Celsius. Storing it this way will help preserve the medication’s effectiveness and safety.

Appearance

Brown ampoule containing a clear liquid that is colorless or pale yellow

Package unit

2mL x 50Amp