Clopiren Tablets (Clopidogrel Sulfate)

Adult dose

1. For patients with ischemic stroke, myocardial infarction, or peripheral arterial disease, clopidogrel is administered orally at a dose of 75 mg once daily. 2. For patients with acute coronary syndrome (unstable angina or non-Q-wave myocardial infarction), initiate treatment with a loading dose of 300 mg once daily on the first day with this medication, and then maintain at 75 mg once daily thereafter. At this time, aspirin 75

This medication is an antiplatelet agent that prevents blood platelets from aggregating to avoid thrombus formation. This medication may not be effective in individuals with genetically reduced function of a specific enzyme (CYP2C19), and in such cases, alternative treatments should be considered. Furthermore, taking this medication alongside drugs that activate specific enzymes can increase the concentration of the active ingredient, thereby raising the risk of bleeding, so concurrent use is not recommended. This medication should not be administered to patients with bleeding, severe liver impairment, individuals allergic to the drug's components, nursing women, and those with certain genetic diseases such as lactose intolerance. For patients at high risk of bleeding or suspected of having bleeding disorders, prompt blood tests should be performed, and it may be necessary to discontinue this medication 5 to 7 days prior to surgery. Caution is needed when this medication is taken together with other antiplatelet agents, anticoagulants, non-steroidal anti-inflammatory drugs, and certain antidepressants, as it can increase the risk of bleeding. During pregnancy, the effects on the fetus might not be significant; however, there may be an increased risk of bleeding during delivery, so discontinuation of the drug before labor is recommended. In nursing mothers, it is unclear whether this medication is secreted in breast milk, so careful consideration is needed to decide whether to continue breastfeeding or stop medication. Elderly patients or those with reduced kidney or liver function may have an increased risk of bleeding, thus requiring dose adjustments and monitoring of patient status. If easy bleeding occurs or bleeding does not stop during treatment, or if symptoms such as frequent bruising or rashes appear, medical consultation should be sought immediately. In case of overdose, bleeding time may be prolonged and bleeding complications may occur, in which case platelet transfusion can partially reverse the drug's effect. This medication is not recommended for use in children as its safety and efficacy have not been sufficiently verified. The medication should be stored out of reach of children, and care should be taken not to transfer it to other containers, as this may alter its quality.

Serious side effects

Urticaria, severe swelling (edema), tightness in the chest, shortness of breath, cold sweat, pallor, severe rash with high fever, blistering, peeling skin, oral/ocular mucosal pain, difficulty breathing or shortness of breath, asthma attack, respiratory distress accompanied by cough and fever, jaundice (yellowing of the skin or eyes), extreme fatigue, sudden and severe headache, lightning-like headache, seizures, disorientation, visual disturbances, paralysis, urine

Mild side effects

• Chest pain
• accidental injury
• influenza-like illness
• pain
• fatigue
• edema
• hypertension
• headache
• dizziness
• abdominal pain

This medication may be sensitive to air and moisture; therefore, it should be stored in a tightly sealed container. Avoid keeping it in extremely hot or cold places, and store it at room temperature between 1 and 30 degrees Celsius.

Appearance

Pink round film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle