Atovastatin 10 mg Tablets (Atorvastatin Calcium Hydrate)

Adult dose

For the treatment of hyperlipidemia, the recommended initial dose is 10 mg once daily. If greater reductions in LDL cholesterol are required, treatment may start at 20 mg or 40 mg once daily. The dosage range is 10 to 80 mg once daily. Both the initial and maintenance doses should be individualized based on treatment goals and responses, with lipid levels analyzed and adjusted 2 to 4 weeks after starting treatment. For homozygous familial hypercholesterolemia, the dosage is 10 to 80 mg once daily, used in conjunction with other lipid-lowering therapies (e.g., LDL apheresis) or when such therapies are not possible. Pediatric patients (ages 10 to 17) with heterozygous familial hypercholesterolemia have a recommended initial dose of 10 mg once daily, with a recommended maximum dose of 20 mg (there is no clinical data for doses higher than 20 mg in this population). The dosage should be adjusted appropriately based on individual treatment goals, with adjustments made at intervals of 4 weeks or more. Patients with renal impairment: Renal conditions do not affect the plasma concentration of atorvastatin or the LDL cholesterol-lowering effect, so there is no need to adjust the dose. Elderly patients: The efficacy and safety in patients over 70 years of age are similar to those in the general adult population.

Child dose

The recommended initial dose for pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17) is 10 mg once daily, with a recommended maximum dose of 20 mg once daily. The dosage should be adjusted appropriately according to treatment goals.

This medication may pose a risk of muscle problems, so if severe muscle pain or weakness occurs, stop taking it immediately and consult a doctor. This medication should not be used by individuals with specific liver diseases, those with muscle disorders, pregnant women, or women who may become pregnant, and children under the age of 10. Individuals with liver function issues, those who consume alcohol heavily, elderly patients, and those with impaired kidney function need to exercise caution when using this medication, and regular tests should be performed to monitor liver and muscle status. If symptoms of liver dysfunction or hepatitis (nausea, vomiting, fatigue, etc.) occur while taking this medication, inform a doctor immediately. This medication has many interactions with other drugs, so inform your doctor or pharmacist of any medications you are currently taking, especially when used with certain antibiotics, antifungals, antivirals, and some cardiovascular drugs. If symptoms such as muscle pain, cramps, weakness, or other muscle-related issues occur during treatment, inform your doctor immediately, and conduct blood tests to check for muscle damage if necessary. Women of childbearing age should use appropriate contraception while on this medication, and if pregnancy is confirmed, they should stop taking it immediately. Breastfeeding women should not take this medication as it can pass into breast milk and cause side effects in the baby. The safety and efficacy of this medication in children and adolescents over the long term have not been sufficiently studied, so caution is advised in its use. There are no specific antidotes for overdose, so treatment should be administered according to symptoms, and regular checks on liver function and muscle status should be performed. This medication should be stored out of reach of children and kept in its original container, as transferring it to another container may pose risks of misuse or deterioration in quality.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attack, cough with fever-related respiratory issues, jaundice (yellowing of skin or eyes), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion of consciousness, vision disturbances, paralysis, urination issues.

Mild side effects

• Fatigue
• malaise
• chest pain
• peripheral edema
• tiredness
• fever
• nasopharyngitis
• hyperglycemia
• hypoglycemia
• weight gain

This medication must be stored in a tightly sealed container to protect it from air and moisture. It is important to maintain a storage temperature between 1 degree and 30 degrees Celsius to keep the medication effective and safe over time.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle