Iranitidine Tablets (Ranitidine Hydrochloride)

Adult dose

For adults, the administration of ranitidine should be 150 mg per dose, taken twice daily, in the morning and at bedtime. 1) For gastric and duodenal ulcers: 150 mg once or twice daily or 300 mg once daily at bedtime; for duodenal ulcer patients, 300 mg may be administered twice daily. 2) For gastroesophageal reflux disease: 150 mg twice daily for 8 weeks or 300 mg once daily before bedtime.

Child dose

For children aged 8 to 18 years, a single dose of 150 mg (2 mg per kg of body weight) may be administered up to twice a day.

This medication should not be used in patients who have had allergic reactions to this medication or its ingredients. It should not be administered to patients with a history of acute porphyria due to the risk of provoking seizures. Furthermore, patients who are genetically unable to break down lactose should not use this medication as it contains lactose. In patients with impaired kidney function, dosage should be reduced or the dosing interval should be increased as this medication may remain in the body for an extended period. Caution is also advised in patients with liver dysfunction. Patients with a history of drug allergies or elderly patients should be administered this medication carefully. Patients taking non-steroidal anti-inflammatory drugs may have an increased risk of gastrointestinal bleeding and should be monitored regularly. Gastric ulcer patients or those with new dyspeptic symptoms in middle age or older should verify malignancy status before use, as this medication may mask gastric cancer symptoms. Patients with Helicobacter pylori-associated gastric or duodenal ulcers should undergo eradication treatment simultaneously. This medication can rarely cause serious allergic reactions, blood abnormalities, liver dysfunction, cardiac rhythm issues, gastrointestinal symptoms, neurological disorders, and skin rashes. If any unusual symptoms occur, take the medication off immediately and consult a doctor. It is important to have regular blood, liver, and kidney function tests during treatment. Elderly patients or those with chronic diseases may be at increased risk of pneumococcal infections and should be cautious. Avoid driving or operating dangerous machinery if dizziness or drowsiness occurs after taking this medication. Be sure to inform your doctor or pharmacist of any other medications being taken due to potential drug interactions, especially with drugs that affect blood coagulation. This medication should be administered cautiously in pregnant or potentially pregnant women and nursing mothers only when necessary. Safety in children has not been fully established, so caution is necessary. This medication is primarily excreted via the kidneys, so elderly patients may require dosage adjustments due to decreased kidney function. Overdose is rarely associated with specific symptoms, but treatment may include vomiting or gastric lavage as appropriate. This medication should be stored out of the reach of children and should not be transferred to other containers. Long-term use may affect the eyes, so it is advisable to undergo ophthalmic examinations.

Serious side effects

Shock (anaphylaxis), angioedema, bronchospasm, severe allergic reactions (urticaria, severe swelling), vascular edema, severe skin reactions (severe rash, blisters, skin peeling, pain in mucous membranes of the mouth/eyes), respiratory issues (difficulty breathing, asthma attacks, cough with fever accompanying respiratory issues), jaundice (yellowing of the skin or eyes, generalized lethargy), severe neurological symptoms (sudden and extremely severe headache)

Mild side effects

Urticaria, rash, fever, hypotension, chest pain, abnormal blood tests (granulocytopenia, leukopenia, thrombocytopenia, eosinophilia), liver dysfunction (increased AST, ALT, γ-GTP, ALP levels), bradycardia, heart block, tachycardia, constipation, nausea, vomiting, abdominal bloating, abdominal pain, loss of appetite, diarrhea, dizziness, drowsiness, headache, heaviness, insomnia, agitation, anxiety, mental confusion, depression, hallucinations, blurred vision, involuntary movements

This medication should be stored in a tightly sealed container that blocks light and in a dry place free from moisture. This storage method will help maintain the efficacy of the medication for a longer period.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 500 tablets/bottle