Medication info
Lovatitan Tablet 20/160 mg

Lovatitan Tablet 20/160 mg

Prescription medicationTablet경구
Ingredient · strength
Valsartan›160mgRosuvastatin Calcium Micronized›20.8mg
Manufacturer / importer
(주)엘지화학
Appearance
Brown oval film-coated tablets
Packaging
56 tablets (14 tablets/PTP x 4)
Approval status
Active

MFDS item code 201309652 · Approved 2013.10.10 · Insurance code 668902660

Summary

Main use
Effect of reducing the risk of cardiovascular diseases such as treatment of hypertension and heart failure, improvement of hypercholesterolemia
Who takes it
Adults
Adult dose
◆ Valsartan 1. Essential Hypertension Take with water during meals or between meals. It is recommended to take it at the same time each day (e.g., in the morning) if possible. Adults: The recommended oral dose is 80 mg once daily. Patients whose blood pressure is not well controlled may increase the dose to 160 mg per day or may take it in conjunction with a diuretic, with a maximum possible increase to 320 mg. 2. Heart Failure Adults: The initial oral dose recommended is 40 mg, taken twice daily, which may be increased to 80 mg or 160 mg per dose.

Ingredients

Manufacturer
(주)엘지화학

Efficacy & effects

Effect of reducing the risk of cardiovascular diseases such as treatment of hypertension and heart failure, improvement of hypercholesterolemia

  • Essential hypertension
  • heart failure
  • left ventricular failure
  • left ventricular systolic dysfunction
  • primary hypercholesterolemia
  • heterozygous familial hypercholesterolemia
  • combined hyperlipidemia
  • homozygous familial hypercholesterolemia
  • dysbetalipoproteinemia
  • increased high-sensitivity C-reactive protein
  • hypertension
  • low HDL cholesterol levels
View approved original text

This medication contains two active ingredients, valsartan and rosuvastatin, used for specific patients. Valsartan is mainly used for patients with essential hypertension and heart failure, and to reduce the risk of death after myocardial infarction. It is particularly effective for heart failure patients intolerant to ACE inhibitors. Rosuvastatin is used as an adjunct therapy for patients with hypercholesterolemia and dyslipidemia and helps with homozygous familial hypercholesterolemia. It is also used to reduce the risks of stroke, myocardial infarction, and revascularization due to cardiovascular diseases. This medication works synergistically to improve cardiovascular health through the management of blood pressure and blood lipids.

How to take

Adult dose

◆ Valsartan 1. Essential Hypertension Take with water during meals or between meals. It is recommended to take it at the same time each day (e.g., in the morning) if possible. Adults: The recommended oral dose is 80 mg once daily. Patients whose blood pressure is not well controlled may increase the dose to 160 mg per day or may take it in conjunction with a diuretic, with a maximum possible increase to 320 mg. 2. Heart Failure Adults: The initial oral dose recommended is 40 mg, taken twice daily, which may be increased to 80 mg or 160 mg per dose.

Precautions

This medication can cause serious harm to the fetus if taken during pregnancy, particularly during the second and third trimesters, so it should be discontinued immediately upon confirmation of pregnancy. It is safer not to use this medication in women who are allergic to it, pregnant or possibly pregnant, or breastfeeding. Patients with severe liver or kidney dysfunction, muscle diseases, or a history of specific angioedema should not take this medication. Elderly patients or those with high potassium levels, or with impaired liver function should exercise extra caution while taking this medication, and liver function tests should be repeated as needed. This medication may cause muscle pain, muscle weakness, and rarely severe muscle damage (rhabdomyolysis); therefore, if any unusual muscle symptoms occur, it is important to inform healthcare professionals immediately. While taking this medication, liver function tests and muscle enzyme level tests may be required, and usage should be suspended if there are any abnormal signs. Drug interactions may occur when taken with other medications, so it is essential to inform the physician or pharmacist of any other medications being taken. This medication lowers blood pressure and may cause symptoms of hypotension (dizziness, fainting, etc.), so caution is advised while driving or operating machinery. There are no specific antidotes for overdose, so it is important to avoid exceeding the recommended dose, and to visit a healthcare facility immediately if unusual symptoms occur. It is advisable to avoid use in children and adolescents as the safety and efficacy of this medication have not been adequately established. This medication should be kept out of the reach of children and should not be transferred to another container.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), angioedema (swelling of the face, lips, throat, tongue), tightness in chest, difficulty breathing, angiopathy, vasculitis, serum sickness, hepatitis, hepatic impairment (jaundice), hepatitis, severe skin reactions (Stevens-Johnson syndrome, severe skin reactions), shock, fainting, loss of consciousness, severe neurological symptoms (severe headache, altered consciousness, seizures), rhabdomyolysis, acute renal failure, renal failure, hypertension

Mild side effects

Dyspepsia, nausea, dizziness, headache, conjunctival hemorrhage, constipation, asthenia, chest pain, facial swelling, peripheral edema, nasopharyngitis, urinary tract infection, bruising, increased serum aminotransferases (AST, ALT), increased serum creatine phosphokinase, increased serum potassium, increased gamma-glutamyl transferase, musculoskeletal stiffness, limb pain, sensory loss, anxiety, upper respiratory tract infection, pharyngitis, tonsillitis, spinal stenosis, insomnia

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to light and should be stored in a container that protects it from light. Additionally, it is recommended to store the medication at room temperature between 1 to 30 degrees Celsius. Proper storage helps maintain the medication's effectiveness and safety.

Appearance and packaging

Appearance

Brown oval film-coated tablets

Package unit

56 tablets (14 tablets/PTP x 4)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.