Myal Injection (Sodium Hyaluronate)

Adult administration

Typically, for adults, 1 vial is injected once a week for 3 consecutive weeks into the knee joint space or the shoulder joint (shoulder joint space, subacromial bursa or biceps tendon sheath), but the frequency of administration should be adjusted as needed based on symptoms.

This medication should not be used in patients who have experienced an allergic reaction to any of its ingredients. Caution is required for patients who have a history of allergies to other medications or have liver function issues or liver disease history, as liver function abnormalities may occur. If there are skin diseases or infections at the injection site, caution should be taken since this medication is injected into the joint. Severe allergic reactions, including shock, may occur while using this medication. If symptoms arise, administration should be stopped immediately, and appropriate treatment should be provided. Additionally, hypersensitivity reactions such as swelling of the face, rash, and itching may occur, and administration should be stopped for these symptoms. Temporary pain, swelling, redness, warmth, and a feeling of pressure may occur at the injected joint site. Symptoms such as nausea, vomiting, and fever have also been reported occasionally. If there is severe inflammation in the joint, using this medication may exacerbate the inflammation, so it is recommended to use it after the inflammation has subsided. After administration, caution is needed to stabilize the joint area, and if the medication leaks out of the joint during injection, it may cause pain, so injection should be made accurately into the joint. Injections must be performed under strict aseptic conditions, and if symptoms do not improve, administration should be stopped after 3 doses. If there is a large amount of joint fluid, aspiration may be necessary before injection. This medication should not be administered intravascularly or used for ophthalmic purposes, and appropriate needles should be used. Also, caution should be taken as precipitation may occur when mixed with certain antiseptics. Administration should be done cautiously in women who are pregnant or may become pregnant, and breastfeeding should be avoided during administration. Safety for pediatric use is not established, so it should be used cautiously only when necessary. Elderly patients may have decreased physical function, so administration should be carried out with caution.

Serious side effects

• Hives
• swelling
• shock symptoms

Mild side effects

• Swelling (facial, eyelid, etc.)
• facial flushing
• rash
• itching
• transient pain
• swelling
• redness
• warmth
• local pressure
• nausea

This medication should be stored in a sealed container to prevent air or moisture ingress. The storage temperature should be maintained at room temperature between 1 degree and 30 degrees Celsius to safely preserve the medication's efficacy.

Appearance

A colorless, transparent, and viscous liquid contained in a glass vial (pre-filled syringe) sealed with rubber plugs at both ends.

Package unit

2ml/vial × 3 vials