Siamlorpin Tablets (Amlodipine Besylate)

Adult dose

5 mg daily of Amlodipine, administered orally once a day; the dose may be increased to a maximum of 10 mg per day according to patient response. Adjust accordingly based on age and symptoms.

This medication should not be used in certain patients. It should not be administered to patients with allergies to this drug or similar drugs, nursing women, patients with severe liver dysfunction, severe aortic stenosis, and patients in shock. Additionally, it should be used with caution in certain patients. Care should be taken with patients who have severe hypotension, require dialysis for renal failure, elderly patients, and women who are pregnant or may become pregnant. This medication is generally well tolerated, but various side effects may occur infrequently. The most common side effects include facial flushing, fatigue, swelling, palpitations, dizziness, headache, drowsiness, abdominal pain, and nausea. Less commonly reported are hypotension, vasculitis, neurological symptoms, erectile dysfunction, gynecomastia, gastrointestinal problems, elevated blood sugar, joint pain, muscle pain, blood disorders, skin rashes, and allergic reactions. Caution is needed when using this drug in patients with heart failure, as it may worsen pulmonary edema. In patients with liver dysfunction, the half-life of the drug may be prolonged, requiring dose adjustments. This medication takes effect gradually and is not suitable for acute angina or urgent situations. It is not known to have a significant impact on driving or machine operation abilities. This medication may interact with several other drugs, especially certain antibiotics, antihypertensives, antacids, alcohol, and grapefruit juice. It is advisable to avoid combining it with grapefruit juice as it may significantly increase the drug's effect. Safety has not been established for pregnant women, and alternative medications are recommended if possible. Nursing mothers are advised to discontinue breastfeeding while taking this medication. In children (over 6 years), it also has blood pressure control effects, but safety and efficacy have not been established in children under 6 years old. Overdose may result in severe hypotension, tachycardia, and shock, requiring immediate emergency treatment. This medication is not removed by dialysis, which may necessitate other treatment methods in case of overdose.

Serious side effects

• Hives
• angioedema
• toxic epidermal necrolysis
• jaundice
• hepatitis
• severe allergic reactions
• severe skin reactions
• liver abnormalities
• severe swelling or urination issues.

Mild side effects

• Flushing
• fatigue
• swelling
• palpitations
• dizziness
• headache
• drowsiness
• abdominal pain
• nausea
• lethargy

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is also recommended to store the drug at room temperature, ideally between 1 degree and 30 degrees Celsius, avoiding excessive heat or cold.

Appearance

White octagonal tablet

Package unit

30 tablets/bottle, 300 tablets/bottle