Tripheson Tablet (Eperison Hydrochloride)

Adult dose

Administer 50mg of eperison hydrochloride orally three times a day after meals. Adjust according to age and symptoms.

This medication should not be used in patients with hypersensitivity or those with myasthenia gravis. Additionally, since this drug contains lactose, it should not be administered to patients with genetic conditions such as lactose intolerance, lactose enzyme deficiency, or glucose-galactose malabsorption. Patients with a history of hypersensitivity to medications or liver function impairment should use this drug with caution, as liver function may worsen. Rarely, shock reactions may occur, so symptoms should be closely monitored during administration, and if abnormalities in liver function tests (ALT, AST, ALP) or renal function indicators (proteinuria, BUN) are found, administration must be stopped immediately and appropriate measures taken. Adverse effects such as anemia, skin rash, itching, insomnia, drowsiness, headache, limb paralysis, body stiffness, nausea, vomiting, loss of appetite, abdominal pain, urinary retention, incontinence, weakness, dizziness, facial flushing, sweating, and edema may occur; thus, it is essential to consult a professional if these symptoms arise. In particular, serious skin adverse reactions such as toxic epidermal necrolysis and mucocutaneous-ocular syndrome (Stevens-Johnson syndrome) can occur, so if symptoms such as fever, erythema, blisters, itching, eye congestion, or stomatitis appear, discontinue use immediately and seek medical attention. Drowsiness, dizziness, and weakness may occur while taking this medication, so dosage should be reduced or stopped if these symptoms occur. This medication may cause drowsiness or impaired concentration, so caution is advised when driving a vehicle or operating hazardous machinery. When taken with similar drugs like tolperisone hydrochloride or methocarbamol, adjustment disorders may occur, requiring careful monitoring when combined. Pregnant women or women who may become pregnant should only use this drug if the therapeutic benefit outweighs the risks, as safety has not been established, and breastfeeding should be avoided if possible; if necessary, breastfeeding should be discontinued. Safety in children has not been sufficiently confirmed, so careful use is necessary, and elderly patients may also require dosage adjustments due to declining physical function.

Serious side effects

Shock, hepatic dysfunction (increased ALT, AST, ALP), renal dysfunction (increased proteinuria, BUN), anemia, anaphylaxis, angioedema, toxic epidermal necrolysis and mucocutaneous-ocular syndrome (Stevens-Johnson syndrome), severe skin rash with fever, blisters, skin peeling, mucosal pain in the mouth/eyes

Mild side effects

• Rash
• itching
• insomnia
• drowsiness
• headache
• body stiffness
• limb tremors
• nausea
• vomiting
• loss of appetite

Store this medication in a tightly sealed container to prevent air entry, and it is advisable to keep it at room temperature, between 1 to 30 degrees Celsius. This will help maintain the drug's effectiveness and prevent degradation.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 500 tablets/bottle