Alpiroxofen Tablets (Sodium Loxoprofen Hydrate)

Adult dose

1. For indications 1 and 2: Adults: Administer 60 mg of sodium loxoprofen (anhydrous) orally three times a day. For single dose therapy, administer 60 to 120 mg orally. 2. For indication 3: Adults: Administer 60 mg of sodium loxoprofen (anhydrous) orally. Generally, it can be given twice a day, with a maximum of 180 mg per day.

This medicine should be discussed with a doctor or pharmacist if taken by individuals who regularly consume more than three alcoholic beverages a day, as it may cause gastrointestinal bleeding. This drug can increase the risk of cardiovascular diseases, so individuals with a history of heart diseases or strokes, or those with risk factors, should use it more cautiously. There is a risk of developing ulcers or bleeding in the stomach, so particularly elderly individuals or those with a history of gastrointestinal disorders should exercise caution when taking this medication. Individuals with peptic ulcers, severe blood disorders, liver dysfunction, kidney dysfunction, heart failure, or allergies to this drug or its components should avoid using this medication. Individuals with a history of asthma, hives, or allergic reactions, and women in late pregnancy or breastfeeding should also avoid taking this drug. If symptoms of skin rash, itching, hives, difficulty breathing, or low blood pressure occur during treatment, the medication should be stopped immediately, and medical attention sought. If gastrointestinal symptoms such as abdominal pain, nausea, vomiting, or blood in the stool occur, immediately discontinue use and seek treatment. This medication may cause neurological symptoms such as drowsiness, dizziness, or headaches, so caution is needed when driving or operating machinery. Those with liver or kidney issues, or those with hypertension, heart failure, or bleeding disorders, should undergo regular tests while taking this medication. Taking this drug with other non-steroidal anti-inflammatory drugs may increase the risk of side effects, so it is recommended not to combine them. This medication may interact with certain antidiabetic agents, antibiotics, antihypertensive drugs, anticoagulants, etc., so it is essential to inform healthcare providers about any other medications being taken. Exercise caution during the early and middle stages of pregnancy, and it should absolutely not be taken in the late stages of pregnancy as it may harm the fetus. Safety for children has not been established, so it is generally advised against use in pediatric patients. Elderly patients are at higher risk of adverse reactions, so additional caution is required during use. This drug should be kept out of reach of children and should not be transferred to other containers.

Serious side effects

Hives, severe swelling (edema), tightness in the chest, difficulty breathing, cold sweat, pallor, severe allergic reactions, high fever with severe rash, blisters, skin peeling, pain in oral/ocular mucosa, severe dermatologic reactions, asthma attacks, respiratory issues concurrent with cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, liver abnormalities (jaundice), sudden and severe headaches, thunderclap headache.

Mild side effects

• Rash
• itching
• fever
• abdominal pain
• discomfort in the upper abdomen
• loss of appetite
• nausea
• vomiting
• diarrhea
• constipation

This medication must be stored in a sealed container to prevent exposure to air or moisture. Furthermore, it should be kept at room temperature between 1°C and 30°C.

Appearance

Pink round tablets

Package unit

30 tablets/bottle, 500 tablets/bottle