Gridm Tablet 2/500 mg

Adult dosage

This medication should be taken 1-2 times per day before meals or with meals. The dosage can be adjusted based on the patient’s current treatment regimen, effectiveness, and tolerance, and appropriate blood glucose monitoring should be conducted. Treatment typically begins at a low dose, which can be adjusted based on the medications the patient is currently taking and their blood sugar levels. The initial dosage is glimepiride/metformin hydrochloride 2 mg/500 mg.

This medication can cause severe lactic acidosis or hypoglycemia; therefore, it should be temporarily discontinued and the doctor should be informed if renal function deteriorates abruptly or dehydration occurs. Patients with impaired renal function, severe liver dysfunction, pregnant or breastfeeding women, and those with certain cardiovascular diseases should not use this medication. Patients at high risk for hypoglycemia, such as the elderly, those with poor nutritional status or irregular meals, and those who consume alcohol heavily, should take particular care when using this medication. This medication may cause gastrointestinal symptoms (diarrhea, nausea, vomiting, etc.), and severe symptoms may pose a risk of dehydration, so caution is warranted. Regular blood tests and kidney function evaluations are recommended, and monitoring vitamin B12 levels is also advisable. Drug interactions may occur when taken with other medications, so patients should inform their physician or pharmacist of any other medications they are taking. Alcohol consumption can increase the risk of side effects from this medication, so excessive drinking should be avoided during use. If surgery or radiological contrast tests are to be performed, this medication should be temporarily discontinued, and use should resume only after confirming normal renal function. If symptoms of hypoglycemia (headache, fatigue, tremors, dizziness, etc.) occur, immediate intake of glucose is necessary, and in severe cases, medical help should be sought. Pregnant women should avoid this medication as it may harm the fetus, and breastfeeding women should also avoid it or discontinue breastfeeding. Children and the elderly should have their renal function and overall condition closely monitored while on this medication, with particular caution to not exceed the maximum dose in the elderly. In case of overdose, severe hypoglycemia or lactic acidosis may occur, requiring immediate medical treatment. Caution is needed when driving or operating machinery, as hypoglycemia or impairment of agility may occur.

Serious side effects

Urticaria, severe swelling (edema), difficulty breathing, chest tightness, dehydration due to diarrhea and vomiting, jaundice, severe allergic reactions, serious skin reactions, severe hypoglycemia, lactic acidosis (decreased blood pH, increased plasma lactate concentration), thrombocytopenic purpura, severe thrombocytopenia, liver failure, severe neurological symptoms (headache, seizures, altered consciousness, visual disturbances, paralysis), significant reduction in urine output, severe edemas.

Mild side effects

Diarrhea, nausea, vomiting, abdominal distension, loss of appetite, indigestion, constipation, abdominal pain, temporary visual impairment due to changes in blood sugar levels, erythema, itching, rash, discomfort, metallic taste, thrombocytopenia, leukopenia, hemolytic anemia, erythrocytopenia, agranulocytosis, pancytopenia, decreased vitamin B12, elevated liver enzymes, liver function impairment, hepatitis, allergic vasculitis, photosensitivity of the skin, serum sodium concentration changes.

This medication should be kept in a tightly sealed container to prevent air exposure, and it is recommended to store it at a temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the drug's efficacy.

Appearance

White oblong film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle