Medication info
Exgen Tablet 5/80 milligrams

Exgen Tablet 5/80 milligrams

Prescription medicationTablet경구
Ingredient · strength
Valsartan›80mg / 1 tabletAmlodipine Besylate›6.94mg / 1 tablet
Manufacturer / importer
건일바이오팜주식회사
Appearance
Dark yellow round film-coated tablet
Packaging
28 tablets/box [(14 tablets/PTP x 2)], 30 tablets/bottle
Approval status
Active

MFDS item code 201309147 · Approved 2013.08.30 · Insurance code 073000480

Summary

Main use
Improvement in blood pressure control of essential hypertension through the combination of amlodipine and valsartan
Who takes it
Adults · Children
Adult dose
The recommended dosage for this medication is one tablet once daily, to be taken with water regardless of meals. It is recommended to take it at the same time each day (e.g., in the morning) if possible.
Child dose
The safety and efficacy of this medication have not been established in pediatric patients under the age of 18, so it is not recommended.

Ingredients

Manufacturer
건일바이오팜주식회사

Efficacy & effects

Improvement in blood pressure control of essential hypertension through the combination of amlodipine and valsartan

  • Essential hypertension
View approved original text

In patients with essential hypertension whose blood pressure is not adequately controlled with monotherapy of amlodipine or valsartan, the combination of both medications can effectively control blood pressure. This treatment helps to stably lower blood pressure and reduce the risk of cardiovascular complications. Proper blood pressure management plays an important role in preventing serious complications such as stroke and myocardial infarction. Therefore, this product is used for the treatment of essential hypertension.

How to take

Adult dose

The recommended dosage for this medication is one tablet once daily, to be taken with water regardless of meals. It is recommended to take it at the same time each day (e.g., in the morning) if possible.

Child dose

The safety and efficacy of this medication have not been established in pediatric patients under the age of 18, so it is not recommended.

Precautions

This medication may cause serious harm to the fetus or newborn if taken during the second and third trimesters of pregnancy, and it should be discontinued immediately upon confirmation of pregnancy. The medication should not be used by individuals who are allergic to any of its components, pregnant or breastfeeding women, or patients with severe kidney or liver diseases. Patients with sodium or fluid depletion should stabilize their condition before taking this medication, and suitable measures should be taken if hypotension occurs. Patients with high potassium levels should be cautious when using this medication along with potassium supplements or drugs that can increase potassium levels, and blood potassium levels should be monitored frequently. Patients with renal vascular issues or those who have undergone kidney transplants should carefully observe for changes in kidney function while taking this medication. If symptoms of angioedema such as swelling of the face, lips, or tongue occur while taking this medication, it should be discontinued immediately and not be re-administered. Patients with heart failure or those after a myocardial infarction should periodically check kidney function and blood pressure changes while taking this medication and should be wary of potential heart failure worsening. This medication may interact with other antihypertensive agents or specific medications, so if taking any other medications, one must consult a physician or pharmacist. Caution is advised when driving or operating machinery, as dizziness or fatigue may occur. Pregnant women or those planning to become pregnant should avoid taking this medication, and breastfeeding mothers are also advised against its use. The safety and effectiveness of this medication have not been adequately established in pediatric patients or adolescents under 18 years of age, and its use is not recommended.

Side effects and when to seek care immediately

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attack, respiratory distress accompanied by cough and fever, jaundice (yellowing of the skin or eyes), profound lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination changes

Mild side effects

  • Headache
  • dizziness
  • drowsiness
  • orthostatic dizziness
  • paresthesia
  • lightheadedness
  • tinnitus
  • tachycardia
  • palpitations
  • syncope
Show 28 more
  • orthostatic hypotension
  • hypotension
  • cough
  • pharyngitis and laryngitis
  • diarrhea
  • nausea
  • abdominal pain
  • constipation
  • thirst
  • rash
  • erythema
  • sweating
  • pruritus
  • joint swelling
  • back pain
  • arthritis
  • muscle cramps
  • weakness
  • increased urination
  • polyuria
  • erectile dysfunction
  • edema
  • dependent edema
  • facial swelling
  • peripheral edema
  • fatigue
  • flushing
  • asthenia

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to protect it from air and moisture. Additionally, it is advisable to keep it at room temperature, which should not be too hot or too cold, specifically between 1 to 30 degrees Celsius.

Appearance and packaging

Appearance

Dark yellow round film-coated tablet

Package unit

28 tablets/box [(14 tablets/PTP x 2)], 30 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

No questions yet.

For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.