Exfor Tablet 5/160 mg

Adult dose

The recommended dosage of this medication is 1 tablet once daily, taken with water regardless of meals. It is advisable to take it at the same time each day (e.g., in the morning). There are formulations of 5/80 mg, 5/160 mg, and 10/160 mg, administered according to patients whose blood pressure is not controlled by individual components. For patients with renal impairment, dosage adjustment is not necessary for mild to moderate renal impairment (creatinine clearance greater than 10 mL/min). However, the use of this medication is contraindicated in patients with severe renal impairment (creatinine clearance less than 10 mL/min) and those on dialysis. In patients with moderate renal impairment, monitoring of potassium levels and creatinine is recommended.

Child dose

Safety and efficacy in pediatric patients under 18 years of age have not been established; therefore, use of this medication is not recommended.

This medication can cause serious harm or death to the fetus and newborn if taken during the second and third trimesters of pregnancy; therefore, it should be discontinued immediately upon confirmation of pregnancy. Patients with allergies to this drug's active ingredient or similar components, women who are pregnant or may become pregnant, lactating women, and those with severe renal or hepatic dysfunction should not use this medication. Patients who are sodium or volume depleted, those with hyperkalemia, renal artery stenosis, recent kidney transplant recipients, individuals with a history of angioedema, and those with heart failure or post-myocardial infarction should use this medication with caution and closely monitor their condition. Side effects such as dizziness, headache, edema, and hypotension may occur during treatment; if unusual symptoms arise, immediate consultation with healthcare professionals is necessary. Caution is advised when driving or operating machinery, as dizziness or fatigue may occur. There may be drug interactions, especially with potassium supplements, diuretics, certain anti-inflammatory drugs (NSAIDs), simvastatin, and specific antifungal or antiviral agents, so it is important to inform your doctor or pharmacist if you are taking any of these. It is best for women who are pregnant or breastfeeding to avoid using this drug; those planning a pregnancy or suspecting they could be pregnant should consult healthcare professionals. Use in children under 18 is not recommended due to insufficient safety and efficacy data. In case of overdose, severe hypotension or cardiovascular issues may arise, so it is crucial to adhere to the prescribed dosage and contact medical assistance immediately if overdosed. Regular blood pressure and renal function testing should be done while taking this medication, and any unusual symptoms should be reported to healthcare professionals immediately.

Serious side effects

Urticaria, severe swelling (edema), angioedema, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blistering, skin peeling, pain in mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attack, coughing with fever and respiratory issues, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances.

Mild side effects

• Headache
• dizziness
• drowsiness
• paresthesia
• lightheadedness
• tinnitus
• tachycardia
• palpitations
• syncope
• orthostatic hypotension

This medication should be stored in a tightly closed container to prevent exposure to air or moisture. The storage temperature must be maintained between 1 and 30 degrees Celsius room temperature. Proper storage will help maintain the drug's efficacy and prevent degradation.

Appearance

Dark yellow oval film-coated tablets

Package unit

28 tablets/box [14 tablets/Alu-Alu X 2]