Excombi Tablet 10/160 mg

Adult dose

The recommended dose for adults is 1 tablet once daily, to be taken with water regardless of meals. It is advised to take it at the same time every day (e.g., in the morning). For patients with mild to moderate renal impairment, dose adjustment is not necessary. For patients with mild to moderate liver impairment, the daily dosage of valsartan should not exceed 80 mg. For patients with severe renal impairment and dialysis patients, and for patients with severe liver impairment, this medication should not be administered.

Child dose

The safety and efficacy of this medication have not been established in pediatric patients under 18 years of age, so its use is not recommended.

This medication can cause serious harm to the fetus and newborn if taken during the second and third trimesters of pregnancy, so it should be discontinued immediately if pregnancy is confirmed. Patients with allergies to the active ingredient or similar compounds, women who are pregnant or breastfeeding, and patients with severe kidney or liver disease should not take this medication. Patients with sodium or fluid depletion, patients with hyperkalemia, patients with renal artery stenosis, and patients who have recently undergone kidney transplantation require special caution when taking this medication, and close monitoring by healthcare professionals is necessary. Since this medication lowers blood pressure, emergency measures are required if symptoms of hypotension occur, such as laying the patient down and administering saline if necessary. This medication may cause side effects such as headache, dizziness, swelling, fatigue, and skin rash, and if symptoms are severe or persistent, patients should consult their healthcare provider. Caution is needed when driving or operating machinery as dizziness or fatigue may occur. This medication can interact with other antihypertensive drugs, potassium supplements, diuretics, and certain anti-inflammatory drugs (NSAIDs), so patients should inform their healthcare provider of any other medications they are taking. Women who are pregnant or planning to become pregnant should not take this medication, and breastfeeding women are also advised to avoid it. It is not recommended for children under 18 years of age as the safety and efficacy of this medication have not been adequately established in pediatric patients. Severe hypotension or cardiac dysfunction may occur in cases of overdose, so it is crucial to adhere to the prescribed dosage and inform the healthcare provider of any unusual symptoms.

Serious side effects

• Urticaria
• severe swelling (edema)
• angioedema
• vasculitis
• Stevens-Johnson syndrome
• renal failure
• kidney damage
• elevated serum creatinine
• increased liver function levels
• jaundice

Mild side effects

• Headache
• dizziness
• drowsiness
• postural dizziness
• sensory disturbances
• lightheadedness
• tinnitus
• tachycardia
• palpitations
• syncope

This medication is susceptible to air and moisture, so it should be stored in a tightly sealed container. It is recommended to maintain the storage temperature between 1 and 30 degrees Celsius to safely preserve the effectiveness of the medication.

Appearance

Bright yellow oval film-coated tablet

Package unit

For domestic use: 30 tablets (10 tablets/PTP X 3), for export: 30 tablets (10 tablets/PTP X 3)