Cokids Pen Syrup (Dexibuprofen)

Adult dose

For children over 12 years and adults, those weighing over 43 kg can take 18-25 mL (215-300 mg) at a time, with a maximum daily dosage of 72-100 mL (860-1200 mg). Dosages are distinguished by other age and weight categories. Administration should be every 4-6 hours as needed and should not exceed 4 times per day.

Child dose

Children aged 6 months and older should take a dose of 0.4-0.6 mL/kg (5-7 mg/kg of dexibuprofen) every 4 to 6 hours as needed, not exceeding 4 times per day (28 mg/kg).

This medication should be discussed with a physician or pharmacist before use by individuals who regularly consume more than 3 drinks of alcohol daily, as its use with alcohol may lead to gastrointestinal bleeding. It may pose a risk to the cardiovascular system, so individuals with cardiovascular disease or risk factors should be especially cautious and monitored by a physician. High doses of this drug may increase risks, and its use should be avoided. It can also affect the gastrointestinal tract; therefore, individuals with a history of gastric ulcers or bleeding should be extremely cautious when taking this medication, and seek immediate medical treatment if symptoms of gastrointestinal bleeding or ulcers occur. Persons with peptic ulcers, severe blood, liver, kidney, or heart diseases, or an allergy to any components of this drug, or a history of asthma should not take this medication. Individuals with a history of gastric ulcers, blood disorders, liver or kidney issues, heart failure, hypertension, or allergies should consult with their doctor before taking this medication, particularly the elderly and children who require special attention. While taking this drug, there may be rare occurrences of shock, blood disorders, gastrointestinal abnormalities, skin rashes, liver function abnormalities, hypersensitivity reactions, visual disturbances, neurological issues, kidney function decline, and cardiovascular problems, so immediate consultation with medical personnel is advised upon experiencing symptoms. If long-term use of this medication is necessary, regular blood tests, liver function tests, and kidney function tests should be performed to check for abnormalities, and the duration of administration and dosage should be kept to a minimum. This medication can interact with other non-steroidal anti-inflammatory drugs, glucocorticoids, alcohol, certain antihypertensives, anticoagulants, and lithium preparations, so caution is required when taken together. During pregnancy, particularly in the late stages, it may be harmful to the fetus, so it is safer for women who are pregnant or may become pregnant to refrain from using this medication. For breastfeeding women, this medication may be transmitted through breast milk and cause adverse reactions in infants, so breastfeeding should be discontinued or the medication should be stopped. In children, safety has not been established for infants under 6 months, and the minimum necessary dose should be used cautiously while monitoring for adverse reactions. Elderly patients may experience adverse reactions more easily, so treatment should start with a small amount and be closely monitored based on the patient's condition. In cases of overdose, emergency measures such as gastric lavage or inducing vomiting should be sought as quickly as possible, and this medication should be stored out of reach of children and should not be transferred to another container.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor, severe rash with fever, blisters, peeling skin, pain in mouth/eye mucosa, difficulty or trouble breathing, asthma attacks, respiratory abnormality with cough + fever, yellowing of the skin or eyes (jaundice), profound lethargy, sudden and severe headache, lightning headache, seizures, confusion, vision abnormalities, paralysis, urination issues

Mild side effects

• Nausea
• vomiting
• abdominal pain
• indigestion
• diarrhea
• stomach discomfort
• dry mouth
• stomatitis
• abdominal bloating
• constipation

Drug interactions

This medication should not be taken with other non-steroidal anti-inflammatory drugs or high doses of methotrexate. Consult your doctor or pharmacist when taking with glucocorticoids, digoxin, phenytoin, probenecid, sulfinpyrazone, sulfonylureas, diuretics, antihypertensives, ACE inhibitors, furosemide, aspirin, lithium, low doses of methotrexate, and coumarin anticoagulants.

Food interactions

Caution is required when taking this medication with alcohol.

This medication is sensitive to light and should be stored in a tightly sealed container that protects it from light. The ideal storage temperature is between 15 to 25 degrees Celsius to maintain the effectiveness and safety of the drug.

Appearance

A syrup form that is white to pale yellow in color, with a fruity aroma, contained in a brown glass bottle or a white plastic bottle.

Package unit

50 mL/bottle, 100 mL/bottle, 500 mL/bottle