Rosoprine Tablets (Loxoprofen Sodium Hydrate)

Adult dose

1. For indications 1 and 2 ○ Adults: Administer 60 mg of loxoprofen sodium (anhydrous) orally three times a day. For a one-time dose, administer 60-120 mg orally. 2. For indication 3 ○ Adults: Administer 60 mg of loxoprofen sodium (anhydrous) orally. In principle, it can be taken twice a day, with a maximum daily dosage of 180 mg. It is recommended to avoid taking on an empty stomach.

This medication may cause gastrointestinal bleeding in individuals who regularly consume more than three alcoholic drinks per day, so it is essential to consult a doctor or pharmacist. It may increase the risk of cardiovascular diseases, so extra caution is necessary if there are existing heart or vascular conditions or risk factors. As a nonsteroidal anti-inflammatory drug, it may cause serious gastrointestinal issues such as bleeding, ulcers, or perforation. Older adults or those with a history of gastrointestinal issues should be particularly careful. Patients with a history of peptic ulcers, severe liver or kidney impairment, severe heart failure, or those allergic to this medication or similar drugs should not take it. Patients with a history of peptic ulcers, blood disorders, decreased liver or kidney function, heart failure, asthma, or hypertension should use this medication cautiously and monitor their condition closely while taking it. If any unusual symptoms such as rashes, itching, difficulty breathing, gastrointestinal bleeding, abdominal pain, or severe hives occur during treatment, discontinue use immediately and seek medical attention. Long-term use should include regular blood tests, liver function tests, and kidney function tests to check for any abnormalities. It is advisable not to take this medication with other nonsteroidal anti-inflammatory drugs, and it may interact with certain blood pressure medications, anticoagulants, and antibiotics, so it is crucial to inform your physician of any other medications being taken. It is contraindicated in late pregnancy as it may harm the fetus and should be used cautiously in early or mid-pregnancy. It is also safer not to take while breastfeeding. Safety for children has not been established, and older adults are at a higher risk for adverse reactions, so they need to be particularly cautious. Finally, store this medication out of reach of children and avoid transferring it to other containers.

Serious side effects

Hives, severe swelling (including angioedema, facial swelling), tightness in the chest, difficulty breathing, low blood pressure, shock, anaphylaxis-like symptoms, peptic ulcer, perforation, hematemesis, melena, blood in stool, shock-related bleeding, intestinal perforation, severe rashes, skin and mucous membrane syndrome (Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell syndrome), polymorphic erythema, acute generalized exanthematous pustulosis, jaundice, acute kidney failure, nephrotic syndrome, convulsions

Mild side effects

• Occasionally may cause rashes
• itching
• fever
• abdominal pain
• discomfort in the upper stomach
• loss of appetite
• nausea
• vomiting
• diarrhea
• constipation

This medication should be stored in a tightly closed container to protect it from air and moisture, preferably at a temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness for a longer period.

Appearance

White to pale yellow round tablets

Package unit

30 tablets/bottle, 300 tablets/bottle