Megafor 10/160 mg

Adult dosage

The recommended dosage is 1 tablet once daily, taken with water regardless of meals. It is recommended to take it at the same time daily (e.g. morning). If blood pressure is not controlled after dosage adjustments based on individual ingredients, administration should proceed as follows: - 5/80 mg: For patients not adequately controlled with amlodipine 5 mg or valsartan 80 mg as monotherapy.

Children's dosage

Safety and efficacy in pediatric patients under 18 years of age have not been established, and use of this medication is not recommended.

This medication may cause serious harm to the fetus or newborn if taken during the second or third trimester of pregnancy; it should be discontinued immediately once pregnancy is confirmed. It should not be used in patients with an allergy to the active ingredients or similar drug classes, women who are pregnant or breastfeeding, patients with severe kidney or liver disease, or patients with certain heart conditions. Patients who are deficient in sodium or fluid must manage their condition before taking this medication, and if symptoms of hypotension appear, they should be laid down immediately and may require fluid therapy. Patients with high potassium levels should take caution when taking this drug and potassium-increasing medications together, and potassium levels should be monitored frequently. Patients with renal artery stenosis or those who have recently undergone kidney transplantation should use this medication with caution, as it may affect kidney function. If symptoms of angioedema occur, use of the medication should be discontinued immediately, and it should not be readministered. Patients with heart failure or after myocardial infarction should be carefully monitored for changes in kidney function when taking this medication, and it is advisable not to combine it with certain drugs in heart failure patients. This medication may cause various adverse reactions, with common symptoms including headache, dizziness, swelling, fatigue, etc. Caution should be exercised when driving or operating machinery, as dizziness or fatigue may occur. When used in combination with other medications, there may be interactions, so consultation with a doctor or pharmacist is necessary, especially when used with certain antihypertensives, potassium supplements, or specific anti-inflammatory medications. Women who are pregnant or planning to become pregnant should not use this medication, and breastfeeding women are also advised to avoid its use. It is not recommended for children under 18 years of age, as safety and effectiveness have not been sufficiently established. Elderly patients may use similar dosages as adults, but their physical status should be closely monitored. Overdosage may lead to severe hypotension or cardiovascular abnormalities, requiring immediate medical attention. During treatment, it is important to regularly check blood pressure, kidney function, and electrolyte levels.

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucous membranes, shortness of breath or difficulty breathing, asthma attacks, cough with fever accompanied respiratory abnormalities, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, consciousness confusion, visual disturbances, paralysis.

Mild side effects

• Headache
• dizziness
• drowsiness
• orthostatic dizziness
• sensory abnormalities
• lightheadedness
• tinnitus
• tachycardia
• palpitations
• fainting

This medication should be stored in a tightly sealed container to protect it from air and moisture. The recommended storage temperature is room temperature between 1 to 30 degrees Celsius.

Appearance

Bright yellow egg-shaped film-coated tablets

Package unit

28 tablets (14 tablets/PTP packaging X 2), 30 tablets/bottle