Roxocul Tablet (Roxoprofen Sodium Hydrate)

Adult dose

1. For indications 1 and 2 ○ Adults: Administer 60 mg of Roxoprofen Sodium (anhydrous) orally three times a day. In single-dose therapy, administer orally 60-120 mg. 2. For indication 3 ○ Adults: Administer 60 mg of Roxoprofen Sodium (anhydrous) orally. In principle, it can be taken twice daily, with a maximum of 180 mg per day. It is preferable to avoid taking this medication on an empty stomach.

This medication should be discussed with a doctor or pharmacist if taken by individuals who regularly consume more than three glasses of alcohol per day, as it may cause gastrointestinal bleeding. Furthermore, non-steroidal anti-inflammatory drugs (NSAIDs), including this medication, can increase the risk of serious thrombotic reactions such as myocardial infarction or stroke in individuals with cardiovascular issues or risk factors. Therefore, both the doctor and patient should carefully monitor for any symptoms related to the cardiovascular system and report any occurrence immediately. This medication can also affect the gastrointestinal tract, leading to serious issues such as bleeding, ulcers, or perforations in the stomach or intestines. Elderly patients or those with a history of gastrointestinal diseases are at higher risk and should be monitored closely for gastrointestinal symptoms while on this medication. Patients with peptic ulcers, severe blood disorders, liver dysfunction, kidney dysfunction, heart failure, and those allergic to this medication or its components should not take this medication. Additionally, individuals who have had allergic reactions to aspirin or other NSAIDs should not use this medication. Pregnant women in late pregnancy, nursing mothers, and individuals with inflammatory bowel disease should also refrain from taking this medication. Patients with a history of peptic ulcers or liver, kidney, or blood disorders should exercise particular caution when using this medication. If allergic symptoms such as rash, itching, difficulty breathing, or low blood pressure occur during use, the medication should be stopped immediately, and medical help should be sought. Gastrointestinal symptoms may include abdominal pain, nausea, vomiting, diarrhea, or blood in stools; report any of these symptoms immediately. This medication can cause neurological symptoms such as drowsiness, dizziness, or headaches, so caution should be exercised when driving or operating machinery. There may be changes in liver and kidney function, requiring periodic testing, and any unusual symptoms should be reported to healthcare providers immediately. This medication can interact with other NSAIDs or certain medications, so be sure to inform healthcare providers about any other medications being taken. Women who are pregnant or may become pregnant should use this medication with caution and must not take it during late pregnancy. It is also safe to avoid this medication while breastfeeding. Safety in children has not been established, so its use is not recommended in pediatric patients. Elderly patients are at a higher risk of side effects when taking this medication and should be particularly cautious. Finally, this medication should be kept out of reach of children and should not be transferred to another container.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, shock, anaphylactic-like symptoms, gastrointestinal bleeding (hematemesis, melena, blood in stool), shock, Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell's syndrome), acute generalized exanthematous pustulosis, liver dysfunction (including jaundice), fulminant hepatitis, acute renal failure, respiratory distress, asthma attacks, interstitial pneumonia, aseptic meningitis

Mild side effects

• Occasionally may cause rash
• itching
• fever
• abdominal pain
• gastrointestinal discomfort
• loss of appetite
• nausea
• vomiting
• diarrhea
• constipation

This medication may be sensitive to air and moisture, so it should be stored in a sealed container. It is essential to maintain a storage temperature between 1 to 30 degrees Celsius to preserve its efficacy and safety over time.

Appearance

White round tablets

Package unit

30 tablets/bottle, 600 tablets/bottle