Esbufen Tablets (Dexibuprofen)

Adult dose

As dexibuprofen, take 300 mg orally 2-4 times a day. However, do not exceed 1,200 mg of dexibuprofen per day.

This medication should not be taken by individuals who regularly consume more than 3 glasses of alcohol daily due to the risk of gastrointestinal bleeding, and consultation with a doctor or pharmacist is essential. This medication can affect the cardiovascular system and may increase the risk of myocardial infarction and stroke, so individuals with cardiovascular diseases or risk factors should take particular caution. Serious issues such as gastrointestinal bleeding, ulcers, and perforation can occur; therefore, elderly patients or those with a history of gastrointestinal diseases should be cautious when taking this medication. In cases of specific conditions such as gastric ulcers, bleeding, severe liver or kidney impairment, heart failure, hypertension, and asthma, it is safest not to take this medication. Taking this medication in conjunction with aspirin or other non-steroidal anti-inflammatory drugs increases the risk of gastrointestinal bleeding, so co-administration should be avoided. While taking this medication, breastfeeding should be paused or discussed with a doctor, and it may cause dizziness or fatigue, necessitating caution when driving or operating machinery. Blood disorders, liver or kidney function deterioration, hypertension, heart failure, allergy history, the elderly, and children should consult medical personnel before taking this medication. If symptoms such as shock, severe skin rash, breathing difficulties, abnormal liver function, kidney issues, or blood disorders occur during use, discontinue use immediately and consult with medical personnel. This medication should be used at the lowest effective dose and for the shortest duration, and regular blood and liver/kidney function tests are necessary for long-term use. It is advisable not to take this medication after the 6th month of pregnancy due to potential impacts on the fetus, and women who are pregnant or planning to be should consult with a doctor. In cases of overdose, medical attention should be sought immediately, even if symptoms are absent. Store out of reach of children and avoid direct sunlight during storage.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in the mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, jaundice (yellowing of skin or eyes), extreme lethargy, sudden severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination issues

Mild side effects

• Dyspepsia
• abdominal bloating
• heartburn
• diarrhea
• constipation
• loss of appetite
• nausea
• vomiting
• abdominal pain
• discomfort in the upper abdomen

Drug interactions

This medication should not be taken with aspirin, other non-steroidal anti-inflammatory drugs, or high doses of methotrexate used in cancer therapy (15 mg/week or more). Additionally, corticosteroids, alcohol, digoxin, phenytoin, probenecid, sulfinpyrazone, sulfonylureas, ACE inhibitors, angiotensin II receptor antagonists, diuretics, lithium, coumarin anticoagulants (such as warfarin), baclofen, and immunosuppressants should be avoided in combination.

This medication should be stored in a sealed container to prevent air exposure and maintained at room temperature between 1 and 30 degrees Celsius. This helps to preserve the medication's effectiveness and prevent deterioration.

Appearance

Pink round film-coated tablets

Package unit

30 tablets/bottle, 500 tablets/bottle