Medication info
Yunazal Tablet 5/80 mg

Yunazal Tablet 5/80 mg

Prescription medicationTablet경구
Ingredient · strength
Amlodipine Besylate›6.94mg / 1 tabletValsartan›30mg / 1 tablet
Manufacturer / importer
한국유나이티드제약(주)
Appearance
Dark yellow, round film-coated tablet
Packaging
30 tablets/box [30 tablets (10 tablets/PTP x 3)]
Approval status
Active

MFDS item code 201308586 · Approved 2013.07.31 · Insurance code 644308640

Summary

Main use
Improvement of blood pressure control in essential hypertension with combined use of amlodipine and valsartan
Who takes it
Adults
Adult dose
The recommended dosage of this medication is 1 tablet once daily, taken with water regardless of meals. It is recommended to take it at the same time each day (e.g., in the morning). For patients with mild to moderate renal impairment, no dosage adjustment is necessary, whereas patients with severe renal impairment and those on dialysis should not take this medication. In patients with liver impairment, care should be taken not to exceed a daily dosage of 80 mg of valsartan. For patients aged 65 and over, dosage adjustments should be made with caution.

Ingredients

Manufacturer
한국유나이티드제약(주)

Efficacy & effects

Improvement of blood pressure control in essential hypertension with combined use of amlodipine and valsartan

  • Essential hypertension
View approved original text

For patients with essential hypertension, if blood pressure is not sufficiently controlled with monotherapy of amlodipine or valsartan, additional therapeutic options may be necessary. This medication is used to effectively lower blood pressure and reduce the risk of cardiovascular diseases. In difficult cases of blood pressure control, it helps to stabilize blood pressure through combination therapy with other drugs. This can decrease the risk of complications due to hypertension and protect health. This medication is used to improve blood pressure control in essential hypertension.

How to take

Adult dose

The recommended dosage of this medication is 1 tablet once daily, taken with water regardless of meals. It is recommended to take it at the same time each day (e.g., in the morning). For patients with mild to moderate renal impairment, no dosage adjustment is necessary, whereas patients with severe renal impairment and those on dialysis should not take this medication. In patients with liver impairment, care should be taken not to exceed a daily dosage of 80 mg of valsartan. For patients aged 65 and over, dosage adjustments should be made with caution.

Precautions

This medication can cause serious harm to the fetus and newborn when taken during the second and third trimesters of pregnancy, so it should be stopped immediately if pregnancy is confirmed. Do not use this medication in individuals with hypersensitivity to the drug, pregnant or nursing women, patients with severe kidney or liver disorders, and patients with specific heart conditions. Patients who are fluid or sodium deficient or have hyperkalemia, renal artery stenosis, etc., should be carefully monitored due to the risk of hypotension and worsening kidney function when taking this medication. This medication lowers blood pressure, and a sudden drop in blood pressure may cause dizziness or fainting when first taken; therefore, the dosage should be increased gradually while monitoring the patient's condition. During treatment with this medication, side effects such as dizziness, headache, swelling, hypotension, digestive discomfort, rash, etc., may occur, and if any unusual reactions occur, a consultation with a healthcare professional is necessary. Care should be taken as dizziness or fatigue may occur when driving or operating machinery. This medication may interact with other antihypertensive medications, potassium supplements, diuretics, non-steroidal anti-inflammatory drugs (NSAIDs), so it is essential to inform healthcare personnel about other medications being taken. Pregnant or nursing women are advised to avoid this medication, and consultation with healthcare personnel is recommended if planning to become pregnant. This medication is not recommended for children under 18 years as its safety and efficacy have not been established.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), angioedema, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attack, respiratory distress accompanied by cough and fever, yellowing of the skin or eyes (jaundice), profound lethargy, sudden and extremely severe headache, thunderclap headache, seizures, confusion, visual disturbances,

Mild side effects

  • Headache
  • dizziness
  • drowsiness
  • sensory disturbances
  • lightheadedness
  • tinnitus
  • tachycardia
  • palpitations
  • orthostatic hypotension
  • hypotension
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  • cough
  • throat and laryngeal pain
  • diarrhea
  • nausea
  • abdominal pain
  • constipation
  • dry mouth
  • rash
  • erythema
  • sweating
  • itching
  • joint swelling
  • lower back pain
  • arthritis
  • muscle cramps
  • lethargy
  • polyuria
  • nocturia
  • erectile dysfunction
  • edema
  • anasarca
  • facial swelling
  • peripheral edema
  • fatigue
  • flushing
  • asthenia
  • facial flushing
  • nasopharyngitis

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to prevent air or moisture from entering, and it is best stored at room temperature between 1 degree and 30 degrees Celsius. Storing it this way will help maintain the drug's effectiveness safely.

Appearance and packaging

Appearance

Dark yellow, round film-coated tablet

Package unit

30 tablets/box [30 tablets (10 tablets/PTP x 3)]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.