Medication info
Levossartan 2.5/160 Milligrams

Levossartan 2.5/160 Milligrams

Prescription medicationTablet경구
Ingredient · strength
Valsartan›160mg / 1 tabletS-Amlodipine Besylate 2.5 Hydrate›3.74mg / 1 tablet
Manufacturer / importer
안국약품(주)
Appearance
Dark yellow, elongated film-coated tablet
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Active

MFDS item code 201308539 · Approved 2013.07.30 · Insurance code 650204070

Summary

Main use
Improvement of blood pressure control in essential hypertension
Who takes it
Adults · Children
Adult dose
The recommended dosage of this medication is 1 tablet once a day, taken with water regardless of meals. It is advisable to take it at the same time every day (e.g., in the morning). For patients with mild to moderate renal impairment (creatinine clearance of more than 10 mL/min), no dose adjustment is necessary, while patients with severe renal impairment and those on dialysis should not take it. For patients with mild to moderate hepatic impairment, the daily dose of Valsartan should not exceed 80mg.
Child dose
Safety and efficacy for pediatric patients under 18 years of age have not been established, so administration of this medication is not recommended.

Ingredients

Manufacturer
안국약품(주)

Efficacy & effects

Improvement of blood pressure control in essential hypertension

  • Essential Hypertension
View approved original text

This medication is used in patients with essential hypertension who have difficulty controlling blood pressure with monotherapy using S-Amlodipine (Amlodipine) or Valsartan. It primarily helps to stably lower blood pressure, thereby reducing the risk of cardiovascular diseases. It effectively improves blood pressure as an adjunctive treatment when blood pressure is not adequately controlled.

How to take

Adult dose

The recommended dosage of this medication is 1 tablet once a day, taken with water regardless of meals. It is advisable to take it at the same time every day (e.g., in the morning). For patients with mild to moderate renal impairment (creatinine clearance of more than 10 mL/min), no dose adjustment is necessary, while patients with severe renal impairment and those on dialysis should not take it. For patients with mild to moderate hepatic impairment, the daily dose of Valsartan should not exceed 80mg.

Child dose

Safety and efficacy for pediatric patients under 18 years of age have not been established, so administration of this medication is not recommended.

Precautions

This medication can cause serious harm or even death to the fetus and newborn if taken during the second and third trimesters of pregnancy, so it should be discontinued immediately upon confirmation of pregnancy. It should not be used by those allergic to any ingredients in this medication or similar medications, pregnant or breastfeeding women, or patients with severe renal or hepatic dysfunction. Before taking this medication, if there is a deficiency of sodium or fluid in the body, these should be replenished first, and blood pressure and renal function should be carefully monitored. Additionally, patients with hyperkalemia or renal vascular problems should have potassium levels and renal function tested frequently while taking this medication, and should discontinue use immediately if symptoms of angioedema occur. Patients with heart conditions, such as those recovering from heart failure or myocardial infarction, or patients with aortic stenosis should exercise caution while taking this medication and should have regular tests for blood pressure and renal function. This medication may cause side effects such as headache, dizziness, edema, hypotension, cough, abdominal pain, rash, etc., and if symptoms are severe or persist, a consultation with a doctor is recommended. Care should also be taken while driving or operating machinery as dizziness or fatigue may occur. This medication may interact with other antihypertensive medications, potassium supplements, diuretics, non-steroidal anti-inflammatory drugs (NSAIDs), so if you are taking other medications, be sure to inform your healthcare provider. Pregnant or planning to become pregnant women should not use this medication, and breastfeeding women are also advised to avoid it. This medication is not recommended for children under 18 years of age, as its safety and efficacy have not been established in this population. In cases of overdose, dizziness and severe hypotension can occur, so the dosage should be strictly adhered to, and if any abnormal symptoms arise, one should visit a medical institution immediately.

Side effects and when to seek care immediately

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory distress accompanied by cough and fever, jaundice (yellowing of skin or eyes), extreme fatigue throughout the body, sudden and severe headache, thunderclap headache, seizure, confusion, altered vision, paralysis, urination

Mild side effects

  • Nasopharyngitis
  • influenza
  • anxiety
  • headache
  • dizziness
  • drowsiness
  • postural dizziness
  • paresthesia
  • vertigo
  • tinnitus
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  • tachycardia
  • palpitations
  • syncope
  • orthostatic hypotension
  • hypotension
  • cough
  • pharyngeal and laryngeal pain
  • diarrhea
  • nausea
  • abdominal pain
  • constipation
  • thirst
  • rash
  • erythema
  • sweating
  • pruritus
  • joint swelling
  • back pain
  • arthritis
  • muscle cramping
  • asthenia
  • polyuria
  • nocturia
  • erectile dysfunction
  • edema
  • angioedema
  • facial edema

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to protect it from exposure to air and moisture, ideally at temperatures between 1°C and 30°C. Storing it this way can help maintain the medication's effectiveness for a long time.

Appearance and packaging

Appearance

Dark yellow, elongated film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.