Lowtec Plus Tablet 20/12.5 mg

Adult dose

This medication is taken once daily, with one tablet regardless of meals. The dosage is adjusted every 2 to 4 weeks based on the patient’s blood pressure response. Elderly patients should start at the lowest dose, and care should be taken when adjusting the dose based on the patient's renal or cardiac function, comorbidities, and other concomitant medications. In patients with renal impairment, mild and moderate renal impairment (creatinine clearance >30 mL/min) are typically treated with this medication.

Child dose

Safety and efficacy in children have not been established.

This medication can cause serious harm to the fetus and newborn if taken during the second and third trimesters of pregnancy; therefore, it should be discontinued immediately upon confirmation of pregnancy. Patients with allergies to ingredients in this medication or patients with severely impaired kidney or liver function, specific electrolyte imbalances, or certain diseases should avoid using this medication. In patients with diminished blood volume, renal impairment, or heart or liver problems, this medication should be used cautiously, with careful observation for symptoms such as hypotension or changes in kidney function. This medication can affect electrolyte balance, particularly levels of potassium, sodium, calcium, and magnesium, making regular blood tests necessary. Dizziness may occur during treatment, so it’s advisable to avoid driving or operating dangerous machinery. This medication can trigger photosensitivity reactions, increasing the risk of skin cancer, so sun exposure should be limited and protective measures taken. During treatment, attention should be paid to drug interactions, especially when taken with potassium supplements, diuretics, lithium, or non-steroidal anti-inflammatory drugs; a doctor should be consulted in such cases. Nursing women should consult a doctor before use, as this drug can pass into breast milk and affect the baby. Safety and efficacy in children and older adults have not been sufficiently established, so caution is advised. Overdose can lead to symptoms such as hypotension, electrolyte imbalance, and dehydration, necessitating immediate medical attention.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, peeling skin, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attack, respiratory difficulties accompanied by cough and fever, jaundice (yellowing of skin or eyes), extreme fatigue, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, urinary changes

Mild side effects

• Nausea
• vomiting
• dizziness
• headache
• fatigue
• drowsiness
• emotional numbness
• restlessness
• upper respiratory tract infection
• urinary tract infection

This medication should be stored in a tightly closed container to prevent exposure to air and moisture. A cool place with temperatures between 1 and 25 degrees Celsius is suitable for storage.

Appearance

Round film-coated tablets with a reddish-yellow color

Package unit

30 tablets/bottle