SYNEX Tablet 10/160 mg

Adult dosage

The recommended dose of this medication is 1 tablet once daily, taken with water regardless of meals. It is recommended to take it at the same time each day (e.g., in the morning). For patients with mild to moderate renal impairment, no dose adjustment is necessary. However, this medication should not be administered to patients with severe renal impairment or those on dialysis. For patients with mild to moderate liver impairment, the daily dose of valsartan should not exceed 80 mg.

Children's dosage

Safety and efficacy for pediatric patients under the age of 18 have not been established, and the administration of this medication is not recommended.

This medication can cause serious harm to the fetus if taken during pregnancy, especially in the second and third trimesters, so it should be stopped immediately upon confirmation of pregnancy. Patients with allergies to this medication's active ingredients or similar components, pregnant or breastfeeding women, or patients with severe kidney or liver disease should not take this medication. Patients with low sodium or fluid must correct their condition before taking this medication, and blood pressure and condition should be closely monitored during treatment. Patients with high potassium levels or those taking potassium supplements should frequently check potassium concentrations, and patients with poor kidney function should also be cautious. Patients with heart failure or those recovering from myocardial infarction should closely monitor kidney function and blood pressure while on this medication, and caution is also needed for patients with acute myocardial infarction. If symptoms of angioedema occur, the medication should be stopped immediately and not readministered, and it should not be given to patients with a history of angioedema. Caution is needed while driving or operating machinery, as dizziness or fatigue may occur. Overdose can lead to hypotension, dizziness, and in severe cases, shock, necessitating immediate consultation with medical personnel. Additionally, this medication may interact with other antihypertensives, potassium-sparing agents, diuretics, and NSAIDs, so it is crucial to inform healthcare providers of any concurrent medications. Safety and efficacy for pediatric patients under 18 years are not adequately established, and the medication is not recommended for them, but can be administered to elderly patients at standard doses. Patients with poor liver or kidney function require dosage adjustments and regular monitoring. Breastfeeding women are advised to avoid taking this medication.

Serious side effects

Urticaria, severe swelling, chest tightness, difficulty breathing, cold sweat, paleness, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucous membranes, shortness of breath or difficulty breathing, asthma attacks, respiratory distress with cough and fever, jaundice (yellowing of skin or eyes), severe fatigue, sudden and extremely severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, significantly reduced urine output

Mild side effects

• Headache
• dizziness
• drowsiness
• sensory disturbances
• vertigo
• tinnitus
• tachycardia
• palpitations
• fainting
• orthostatic hypotension

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is important to maintain a room temperature between 1 and 30 degrees Celsius. This will help retain the medication's effectiveness over time.

Appearance

Bright yellow oval film-coated tablet

Package unit

28 tablets (14 tablets/PTP x 2)