Medication info
Vdiphine Tablet 5/80 mg

Vdiphine Tablet 5/80 mg

Prescription medicationTablet경구
Ingredient · strength
Valsartan›80mg / 1 tabletAmlodipine Besylate›6.935mg / 1 tablet
Manufacturer / importer
위더스제약(주)
Appearance
Dark yellow round film-coated tablet
Packaging
30 tablets/box [10 tablets/Alu-Alu x 3]
Approval status
Active

MFDS item code 201308495 · Approved 2013.07.30 · Insurance code 660702590

Summary

Main use
Improvement in blood pressure control in essential hypertension with combination of amlodipine and valsartan
Who takes it
Adults · Children
Adult dose
The recommended dose of this medication is 1 tablet once daily, taken with water regardless of meals. It is recommended to take it at the same time each day (e.g., in the morning) if possible.
Child dose
Safety and efficacy for pediatric patients under 18 years of age have not been established, hence the administration of this medication is not recommended.

Ingredients

Manufacturer
위더스제약(주)

Efficacy & effects

Improvement in blood pressure control in essential hypertension with combination of amlodipine and valsartan

  • Essential hypertension
View approved original text

Patients are in a situation where monotherapy with amlodipine or valsartan alone is insufficient for blood pressure control. In this case, using both medications together can enhance the blood pressure control effect. Thus, combining amlodipine and valsartan helps lower and manage blood pressure more effectively. This combination therapy plays an important role in reducing the risk of complications associated with hypertension. Therefore, this treatment is used to improve blood pressure control.

How to take

Adult dose

The recommended dose of this medication is 1 tablet once daily, taken with water regardless of meals. It is recommended to take it at the same time each day (e.g., in the morning) if possible.

Child dose

Safety and efficacy for pediatric patients under 18 years of age have not been established, hence the administration of this medication is not recommended.

Precautions

This medication may cause serious harm to the fetus and newborn if taken during the second and third trimesters of pregnancy, so it must be stopped immediately if pregnancy is confirmed. Patients with allergies to any ingredients in this drug, pregnant or breastfeeding women, patients with severe kidney or liver disease, and certain heart disease patients should not take this medication. Patients with low sodium or fluid levels in the body should stabilize their condition before taking this medication, and blood pressure and physical condition should be carefully monitored during treatment. This drug may increase potassium levels, so when taken with potassium supplements or other medications that raise potassium levels, potassium levels should be checked frequently. Patients with issues with renal blood vessels or those who have recently undergone kidney transplant should use this medication cautiously as it may affect kidney function. If symptoms of angioedema such as swelling of the face, lips, or tongue occur while taking this medication, it should be stopped immediately and a doctor notified. Patients who have heart failure or have had a myocardial infarction are at risk of worsening kidney function or low blood pressure while taking this medication, so regular kidney function testing is important. This medication may cause dizziness or fatigue while driving or operating machinery, so caution is advised. Taking this medication with other antihypertensive drugs, diuretics, anti-inflammatory drugs, etc., may influence its efficacy or side effects, so consultation with a doctor is necessary. It is recommended that pregnant and breastfeeding women do not use this medication, and women planning to become pregnant should consult a doctor before taking it. The safety and efficacy in pediatric patients under 18 years of age have not been sufficiently established, so its use is not recommended. In case of overdose, severe hypotension, dizziness, cardiac function abnormalities, etc., may occur, and medical attention should be sought immediately for appropriate treatment.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), angioedema, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, cough with fever combined respiratory symptoms, jaundice (yellowing of skin or eyes), extreme lethargy, sudden severe headache, thunderclap headache, seizures, confusion, visual disturbances

Mild side effects

  • Headache
  • dizziness
  • drowsiness
  • paresthesia
  • vertigo
  • tinnitus
  • tachycardia
  • palpitations
  • syncope
  • orthostatic hypotension
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  • hypotension
  • cough
  • pain in the throat and larynx
  • diarrhea
  • nausea
  • abdominal pain
  • constipation
  • thirst
  • rash
  • erythema
  • sweating
  • itching
  • joint swelling
  • low back pain
  • arthritis
  • muscle cramps
  • weakness
  • polyuria
  • nocturia
  • erectile dysfunction
  • edema
  • angioedema
  • facial swelling
  • peripheral edema
  • fatigue
  • flushing
  • malaise
  • facial flushing
  • rhinitis

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is susceptible to air and moisture, so it should be stored in a tightly closed container. It is advisable to maintain the storage temperature between 1 to 30 degrees Celsius. This helps to preserve the efficacy and safety of the drug for a long time.

Appearance and packaging

Appearance

Dark yellow round film-coated tablet

Package unit

30 tablets/box [10 tablets/Alu-Alu x 3]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.