Iyeon Clopidogrel Hydrogen Sulfate Tablet

Adult dose

○ Adults 1. In patients with ischemic stroke, myocardial infarction, or peripheral arterial disease, administer clopidogrel 75 mg orally once daily. 2. In patients with acute coronary syndrome (unstable angina or non-Q-wave myocardial infarction), begin with a loading dose of 300 mg of this medicine once on the day treatment is initiated, followed by a maintenance dose of 75 mg orally once daily. In this case, aspirin 75 ～ 325 mg should be administered concomitantly with this medicine once daily. 3. In patients with atrial fibrillation, administer 75 mg of this medicine orally once daily. In this case, aspirin 75 ～ 100 mg should be administered concomitantly with this medicine once daily. ○ Patients with renal impairment: Treatment experience in patients with renal impairment is limited. ○ Patients with hepatic impairment: Treatment experience in patients with moderate hepatic disease and a bleeding diathesis is limited. This medicine may be administered with or without food.

This drug is intended to prevent the aggregation of platelets in the blood, thereby preventing the formation of thrombus. Individuals with genetically reduced function of a specific enzyme (CYP2C19) may experience decreased effectiveness of this drug, and in such cases, alternative treatment options should be discussed with a physician. Taking this drug alongside medications that activate the CYP2C19 enzyme may increase the risk of bleeding, so it is advisable not to combine them. This drug should not be used by patients allergic to this medication or its components, patients with bleeding, patients with severely impaired liver function, nursing women, or those with specific genetic diseases. Patients at high risk of bleeding or those scheduled for surgery should use this drug cautiously and may need to discontinue use 5 to 7 days before surgery, if necessary. Since this drug can cause bleeding, any symptoms of bleeding should be reported to a doctor immediately. There may be an increased risk of bleeding when taken with other bleeding risk medications (e.g., warfarin, aspirin, non-steroidal anti-inflammatory drugs, selective serotonin reuptake inhibitors, etc.). It is recommended that pregnant women discontinue use before delivery due to the risk of bleeding, and if nursing, they should consult a doctor about whether to stop breastfeeding due to possible secretion of the drug in breast milk. Safety in children has not been established, so it is advisable not to use it for them. Elderly patients should take this medication cautiously under a doctor's guidance due to decreased bodily function and a higher risk of bleeding and other side effects. Overdose can increase the risk of bleeding, and there is no specific antidote, so platelet transfusions may be necessary to stop the bleeding. This drug should be kept out of the reach of children and should not be transferred to other containers.

Hemorrhage, gastrointestinal bleeding, hospitalization-required bleeding, purpura, contusion, hematoma, epistaxis, hematoma, hematuria, intraocular hemorrhage, intracranial hemorrhage, significant hemorrhage, life-threatening hemorrhage, fatal hemorrhage, hemorrhagic stroke, need for anticoagulants, need for transfusion, substantial degree of functional impairment, intraocular hemorrhage accompanied by significant vision loss, minor bleeding, severe neutropenia, aplastic anemia, severe thrombocytopenia, thrombocytopenia, reduced platelet count, thrombocytopenia, agranulocytosis, myelotoxicity, gastrointestinal symptoms, abdominal pain, dyspepsia, gastroenteritis, constipation, diarrhea, rash, pruritus, depression, upper respiratory tract infection, shortness of breath, rhinitis, bronchitis, cough, urinary tract infection, reduced motor function, tremor, speech disturbance, abnormal gait, hyperkinesia, ataxia, sensory disturbances, insomnia, depression, amnesia, anxiety, confusion, abnormal thoughts, abnormal behavior, arthralgia, myalgia, low back pain, weight loss, weight gain, flushing, fatigue, weakness, rigidity, facial swelling, syncope, purpura, blood in stool, cerebral hemorrhage, gingival bleeding, anemia, cough, shortness of breath, visual disturbances, visual field deficits, dry eyes, temporary blindness, congestion, tinnitus, dysuria, frequent urination, non-protein nitrogen increase, uremia, increased blood urea nitrogen, hypoglycemia, hyperuricemia, elevated liver enzymes, increased ALT, liver dysfunction, leg edema, arrhythmia, bradycardia, palpitations, contact dermatitis, gynecomastia, elevated prostate-specific antigen, loss of appetite, cholecystitis, hematemesis, spinal hematoma, allergic symptoms, ischemic necrosis, hemorrhagic arthropathy, hematuria, hemoptysis, retroperitoneal hemorrhage, postoperative bleeding, pulmonary hemorrhage, vasculitis, hypotension, bronchospasm, interstitial pneumonia, eosinophilic pneumonia, colitis, pancreatitis, gastritis, stomatitis, hepatitis, acute liver failure, herpes zoster, erythematous rash, maculopapular rash, urticaria, angioedema, vesicular dermatitis, drug-induced hypersensitivity syndrome, eosinophilia, drug rash, eczema, lichen planus, glomerulonephritis, gynecomastia, fever, abnormal liver function tests, increased serum creatinine, confusion, hallucinations, taste disturbances, loss of taste, angioedema, Kounis syndrome, anaphylaxis-like reaction, serum sickness, autoimmune syndrome related to insulin, confusion, hallucinations, taste disturbances, loss of taste, vasculitis, hypotension, bronchospasm, interstitial pneumonia, eosinophilic pneumonia, colitis, pancreatitis, gastritis, stomatitis, hepatitis, acute liver failure, herpes zoster, erythematous rash, maculopapular rash, urticaria, angioedema, vesicular dermatitis, drug-induced hypersensitivity syndrome, eosinophilia, drug rash, eczema, lichen planus, glomerulonephritis, gynecomastia, fever, abnormal liver function tests, increased serum creatinine

This drug should be stored in a tightly closed container to prevent air and moisture from entering, and it should be kept at a temperature between 1 and 30 degrees Celsius at room temperature. This will help maintain the effectiveness of the medication.

Appearance

Pink round film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle