Janidin Tablet (Lercanidipine Hydrochloride)

Adult dosage

As Lercanidipine Hydrochloride, the recommended dose is 5 to 10 mg taken orally once daily at least 15 minutes before a meal. Doses may be increased to 20 mg based on the patient's symptoms. Dose adjustment should be made gradually, as the maximum antihypertensive effect will be apparent after approximately two weeks.

This medicine should not be used in certain patients. For example, people who are allergic to this medicine or similar medications, women who are pregnant or may become pregnant, and women who are nursing should not take this medicine. Additionally, patients with heart problems, very poor liver or kidney function, those who have recently experienced a myocardial infarction, patients on dialysis, and children or adolescents under the age of 18 should also not use this medication. This medicine contains lactose, so individuals with lactose intolerance or related genetic diseases should avoid using it. Caution is necessary when using this medicine for some patients. For instance, patients with cardiac rhythm control issues, those with weak heart function, mild to moderate liver or kidney disease, patients with a history of angina, individuals who consume alcohol frequently, and the elderly should use this medicine carefully. During treatment, side effects such as facial flushing, edema, palpitations, dizziness, headache, and indigestion may occur. If any signs of liver dysfunction appear, consult a doctor immediately. Suddenly discontinuing this medicine may worsen symptoms, so the dosage should be gradually reduced while closely monitoring the condition. Moreover, because this medicine is metabolized in the liver, interactions with certain medications can alter its effectiveness. It is particularly crucial to exercise caution when combined with medications affecting liver enzymes, such as certain antifungals, antibiotics, anticonvulsants, and immunosuppressants. Women who are pregnant or breastfeeding are advised against taking this medicine due to reports in animal studies suggesting potential harm to the fetus. The safety and efficacy of this medicine have not been established in children and adolescents, hence it is not prescribed for them. The elderly require special attention while taking this medicine, and dosage adjustments may be necessary. In cases of overdose, severe hypotension and arrhythmias may occur, necessitating immediate medical attention and at least 24 hours of cardiovascular monitoring. Finally, store this medicine out of reach of children, and it is important to keep it in its original packaging to maintain quality.

Serious side effects

Severe allergic reactions (hives, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor), severe skin reactions (rash with high fever, blisters, skin peeling, oral/ocular mucosal pain), respiratory problems (shortness of breath or difficulty breathing, asthma attacks, respiratory irregularities accompanied by cough and fever), liver problems (yellowing of the skin or eyes, extreme lethargy), severe neurological symptoms (sudden and unexpected symptoms)

Mild side effects

Facial flushing, peripheral edema, palpitations, tachycardia, hypotension, chest pain, headache, dizziness, weakness, fatigue, drowsiness, nervous breakdown, indigestion, nausea, vomiting, abdominal pain, diarrhea, increased liver amino transferases, polyuria, frequent urination, gingival hyperplasia, rash, myalgia, tremors, insomnia, dry mouth, hand numbness, cough, abdominal bloating, erectile dysfunction, arrhythmia, cold sweat, tingling of the skin, premature contractions, stiffness of the tongue, increased ventricular premature contractions

This medicine may be sensitive to air and moisture, so it should be stored in a tightly sealed container. Avoid very hot or very cold places, and it is best to store it at a normal temperature between 1 and 30 degrees Celsius.

Appearance

Yellow round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle