KeroXid Tablet (Loxoprofen Sodium Hydrate)

Adult dose

1. For indications 1 and 2: Adults: 60 mg of loxoprofen sodium (anhydrous) is administered orally three times daily. For single therapy, 60–120 mg is administered orally. 2. For indication 3: Adults: 60 mg of loxoprofen sodium (anhydrous) is administered orally. In principle, it can be administered twice a day, with a maximum of 180 mg daily. It is preferable to avoid taking it on an empty stomach.

This drug may cause gastrointestinal bleeding in those who regularly consume more than three alcoholic drinks daily; therefore, consultation with a physician or pharmacist is mandatory. Patients at risk of cardiovascular disease should use this medication cautiously as it may increase the risk of heart disease or stroke, and should consult medical personnel immediately if cardiovascular symptoms occur. This medication can cause severe gastrointestinal side effects such as gastrointestinal bleeding, ulcers, or perforation, so it should be used cautiously in the elderly or patients with a history of gastrointestinal diseases. Patients with a history of peptic ulcers, severe blood disorders, liver impairment, kidney impairment, heart failure, or those allergic to this drug or its components should not use it. Patients with asthma, hives, or a history of allergic reactions should also refrain from taking this drug, and it should not be administered to pregnant women in late pregnancy or nursing mothers. Particular caution is required when administering this drug to patients with a history of peptic ulcers or issues with kidney or liver function. This drug may cause serious side effects such as hypersensitivity reactions like rashes, itching, breathing difficulties, hypotension, gastrointestinal bleeding, liver dysfunction, and renal failure; thus, it should be discontinued immediately and medical personnel consulted if any adverse reactions occur. Regular blood tests and liver and kidney function tests should be conducted for long-term users, and there should be caution for fluid retention or blood pressure changes. Concomitant use with other non-steroidal anti-inflammatory drugs should be avoided as it may increase the risk of side effects. Administration during the early and middle stages of pregnancy should be done cautiously, and it should not be used during late pregnancy under any circumstances. Safety in pediatric patients has not been established, and care should be taken when administering to the elderly.

Serious side effects

Hives, severe swelling (edema), tightness in the chest, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, peeling skin, pain in mucous membranes of mouth/eyes, shortness of breath or difficulty breathing, asthma attack, breathing abnormalities accompanied by cough + fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination issues

Mild side effects

• Rash
• itching
• fever
• abdominal pain
• discomfort in the stomach area
• loss of appetite
• nausea
• vomiting
• diarrhea
• constipation

This medication may be sensitive to air or humidity, so it should be stored in a tightly sealed container. The recommended storage temperature is room temperature between 1 and 30 degrees Celsius. This helps maintain the efficacy of the medication.

Appearance

White round tablet

Package unit

30 tablets/bottle, 300 tablets/bottle, 600 tablets/bottle