Nozyme Capsule 40000 (Pancreatin Enteric-Coated Pellets)

Adult dose

Take 1 capsule (40,000EP units of lipase activity) 3 times daily with meals, with a sufficient amount of water, without chewing. Adjust the dose as appropriate according to each patient's needs, disease severity, and food composition. Do not exceed a dose of 15,000~20,000 EP units of lipase activity per kg of body weight per day. If necessary, for ease of administration, open the capsule and take the contents without chewing. .

This medication should not be taken by individuals allergic to beef or pork. Individuals with allergies to this medication or its components, or those with a history of such experiences, should also avoid taking it. Patients with acute pancreatitis or those whose chronic pancreatitis has suddenly worsened should not take this medication. Patients with cystic fibrosis, pregnant women, or women who might become pregnant must consult a doctor or pharmacist before taking this medication. Nursing women should also consult a healthcare professional before taking this medication since it is unclear if this drug passes into breast milk. Patients taking folic acid preparations should regularly check their folic acid levels as this medication may interfere with folic acid absorption. Patients taking diabetes medications such as acarbose or miglitol should carefully monitor their blood sugar levels as this medication may affect blood sugar control when taken together. If symptoms of allergies, such as skin rash, sneezing, tearing, or bronchospasms occur while taking this medication, it should be discontinued immediately and a healthcare professional consulted. Symptoms such as decreased appetite, dizziness, balance disorders, rhinitis, diarrhea, abdominal pain, nausea, vomiting, dyspepsia, stomatitis, skin rash, and fatigue should prompt discontinuation and consultation with a doctor. Severe side effects such as bowel obstruction or colitis have been reported, particularly in patients with cystic fibrosis, so any unusual abdominal symptoms should be reported to medical staff immediately. In children, care must be taken as ulcers may develop around the mouth and anus. Overdosage of this medication may lead to increased uric acid levels, so the prescribed dosage must be adhered to. This medication is specifically used to improve dyspepsia due to pancreatic disease and should not be used for other purposes. Care should be taken to prevent inhalation of the powder form, as inhalation may cause bronchospasms or rhinitis. If symptoms do not improve after taking this medication for more than 2 weeks, it should be discontinued and a doctor or pharmacist consulted. If dosage adjustments are necessary, they should only be made per a doctor's instructions, based on symptom improvement. This medication should be swallowed whole with water and should not be crushed or chewed. Care must be taken, especially with children, as prolonged retention in the mouth may cause stomatitis or ulcers. Store out of reach of children and keep in a cool, dry place away from direct sunlight. To prevent misuse and maintain quality, do not transfer to another container.

• erythema
• sneezing
• urticaria
• skin rash
• bronchospasm
• loss of appetite
• dizziness
• balance disorder
• rhinitis
• diarrhea

Drug interactions

Consult a doctor or pharmacist if taking this medication with folic acid preparations, acarbose, or miglitol.

This medication should be stored in a tightly sealed container to protect it from air and moisture, and it is best kept at room temperature between 1 and 30 degrees Celsius. Storing it this way helps maintain the medication’s effectiveness.

Appearance

A hard capsule with an opaque brown upper part and an opaque yellow lower part containing enteric-coated pellets with a unique fragrant light brown color.

Package unit

100 capsules/bottle