Alizet Tablets 10 mg (Donepezil Hydrochloride Hydrate)

Adult dose

For Donepezil Hydrochloride, administer 5 mg once daily at bedtime. Administer 5 mg for 4 to 6 weeks and, after evaluating clinical responses, it can be increased to 10 mg. Caution should be taken for gastrointestinal adverse reactions when increasing to 10 mg per day. Underweight women aged 85 years and older should not exceed 5 mg per day and should be closely monitored.

Child dose

There is no experience in using this medication in children.

This medicine contains Donepezil Hydrochloride Hydrate as the main ingredient and is primarily used to improve symptoms of Alzheimer's-type dementia. Firstly, this medication should not be used in certain patients. For example, individuals who are allergic to this drug or its ingredients, women who are pregnant or may become pregnant, and women who are breastfeeding should not take this medication. Additionally, individuals with lactose intolerance or certain genetic metabolic disorders should also refrain from taking this medicine. This drug should be used with caution in individuals with heart diseases or cardiac conduction disorders, as it may slow down heart rate or cause arrhythmias. Patients taking non-steroidal anti-inflammatory drugs or with a history of peptic ulcers should be cautious due to the risk of gastrointestinal bleeding or exacerbation of ulcers. Individuals with a history of asthma or chronic obstructive pulmonary disease may also experience worsening respiratory symptoms while taking this drug, so careful use is necessary. Furthermore, those with extrapyramidal disorders such as Parkinson's disease should exercise caution, as their symptoms may worsen. Various side effects may occur while taking this medication. Cardiac-related issues such as bradycardia, heart block, and myocardial infarction may manifest, while gastrointestinal issues may include gastric ulcers, gastrointestinal bleeding, nausea, vomiting, and diarrhea. Neurological side effects may include dizziness, insomnia, hallucinations, seizures, and movement disorders, and severe adverse reactions such as liver dysfunction or acute renal failure may also occur. Therefore, if these symptoms appear, immediate consultation with a physician is required. The effectiveness of this medication may vary depending on the type of dementia, so it should be taken under the instruction of an experienced physician after an accurate diagnosis. During treatment, regular monitoring of the patient's condition is necessary, and if there is no effect or severe side effects occur, the medication may need to be discontinued. Since this medication can affect driving or machine operation abilities, caution is necessary during the initial phase of medication or when changing dosages. Women who are pregnant or breastfeeding should avoid taking this medication and should consult a healthcare professional if necessary. This medication may interact with various drugs, so if you are taking other medications, be sure to inform your doctor or pharmacist. Special caution is needed when taken with cardiac-related drugs, antidepressants, antibiotics, and anti-inflammatory drugs. In case of overdose, serious symptoms such as vomiting, bradycardia, hypotension, and respiratory depression may occur, and immediate medical treatment is required. Finally, this medication should be stored out of reach of children, and it is safe not to transfer it to other containers.

Serious side effects

Hives, severe swelling (edema), heart block, QT interval prolongation, myocardial infarction, heart failure, peptic ulcer, perforated duodenal perforation, gastrointestinal bleeding, hepatitis, liver dysfunction, jaundice, cerebral seizure (epilepsy, convulsions, etc.), cerebral hemorrhage, cerebrovascular disorders, extrapyramidal disorders (motor function disorders, ataxia, movement disorders, muscle rigidity, tremor, involuntary movements, gait disturbances, abnormal posture, speech disorders), neuroleptic malignant syndrome

Mild side effects

• Loss of appetite
• nausea
• vomiting
• diarrhea
• dizziness
• insomnia
• drowsiness
• headache
• fatigue
• muscle pain

This medication should be stored in a tightly sealed container to prevent air from entering, and it is important to keep it at room temperature between 1 and 30 degrees Celsius. Proper storage will maintain the drug's effectiveness and prevent deterioration.

Appearance

Yellow round film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle