Omeprazole-Duo Dry Syrup (Amoxicillin Trihydrate · Clavulanate Potassium (7:1))

Adult dose

For recurrent tonsillitis and other upper respiratory infections, lower respiratory infections, urinary tract infections, and moderate skin and soft tissue infections, the typical dose of amoxicillin/clavulanate potassium is 25 mg/3.6 mg per kg of body weight divided into two doses per day. In cases of severe infections such as otitis media, sinusitis, or bronchopneumonia, the typical dose of amoxicillin/clavulanate potassium is 45 mg/6.4 mg per kg of body weight divided into two doses per day.

Child dose

7:1 syrup is not suitable for infants under 2 months of age and pediatric patients with renal failure. For children, the dosage should be adjusted based on weight, typically 25 mg/3.6 mg or 45 mg/6.4 mg per day per kg of body weight.

This medication should not be used in patients who have demonstrated hypersensitivity to specific ingredients or beta-lactam antibiotics. Caution should be exercised in cases of allergy to penicillin group drugs due to the possibility of cross-reaction. Patients with viral diseases such as infectious mononucleosis or lymphocytic leukemia may be at a higher risk of rash, and it is advisable to avoid this drug. Patients with a history of liver dysfunction or jaundice due to this medication or penicillins may have a risk of recurrence, so they should not be administered the drug. In patients with impaired liver function or severe kidney disease, the concentration of this drug may increase, necessitating careful dosage adjustment and intervals. Patients with a history of allergies or family history of allergies should consider the potential for allergic reactions to the drug and use it cautiously. Patients who have difficulty swallowing, the elderly, or those in poor general condition may be at risk of bleeding due to vitamin K deficiency, so caution is needed. Patients with severe gastrointestinal symptoms such as vomiting or diarrhea may not absorb the drug properly, hence their condition should be assessed before administration. This drug may cause gastrointestinal side effects such as diarrhea, vomiting, and abdominal pain, and in severe cases, serious complications such as pseudomembranous colitis may occur; therefore, if symptoms appear, the drug should be immediately discontinued, and medical attention should be sought. Abnormalities in liver function tests, hepatitis, or jaundice may occur, especially in elderly males above 60 years of age, necessitating monitoring of liver function during prolonged use. Rarely, serious skin reactions or hypersensitivity responses such as rashes, itching, or shortness of breath may occur; if these symptoms occur, the drug should be discontinued immediately, and emergency care should be provided. Rare blood abnormalities such as leukopenia, thrombocytopenia, or anemia may occur with long-term use, so blood status should be monitored. Central nervous system symptoms such as anxiety, confusion, and seizures have been rarely reported, and risks may increase in patients with poor kidney function or high doses. Avoid use during early pregnancy, and women who are pregnant or nursing should only take this medication after consulting a physician if the benefits outweigh the risks. While nursing, if the baby shows symptoms like diarrhea or skin reactions, the medication should be discontinued. Safety in premature infants or neonates has not been established, so use with caution is necessary. The elderly should use this medication carefully due to an increased risk of adverse reactions associated with decreased bodily functions, necessitating dose adjustments and cautious administration. This drug may interact with other medications, so it is important to inform a physician or pharmacist about any medications being taken, especially when used in combination with anticoagulants or certain antibiotics. In cases of overdose, symptoms may include vomiting, diarrhea, and abdominal pain, and severe cases may involve renal dysfunction or seizures, requiring immediate medical attention. This medication should be stored in a sealed container after preparation and used within 7 days; shake well before use. During the use of this drug, if any unusual symptoms such as diarrhea or abdominal pain appear, promptly consult a physician for appropriate measures.

Serious side effects

Urticaria, severe swelling (angioedema), tightness in the chest, difficulty breathing, cold sweat, pallor, severe allergic reactions (anaphylaxis, anaphylactic shock, hypotension), severe rash with high fever, blistering, skin peeling, pain in the mucous membranes of the mouth/eyes, severe skin adverse reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis, Lyell syndrome), respiratory issues (bronchospasm, laryngeal edema, dyspnea, asthma attack, cough

Mild side effects

• Diarrhea
• pseudomembranous colitis
• dyspepsia
• stomatitis
• gastritis
• glossitis
• black hairy tongue
• nausea
• vomiting
• loss of appetite

This medication may be sensitive to air or moisture, so it must be stored in a sealed container. Additionally, to maintain drug effectiveness, it is recommended to store it in a cool place between 1 and 25 degrees Celsius.

Appearance

A white powder with a distinctive smell that is used to prepare syrup for oral administration.

Package unit

50 mL/bottle