Celecoxib Capsule (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted for each patient and may be taken with or without food. ○ Adults: 1. Osteoarthritis (degenerative arthritis): Take celecoxib 200 mg once daily, or 100 mg per dose twice daily. 2. Rheumatoid arthritis: Take celecoxib 100 mg or 200 mg per dose twice daily. 3. Ankylosing spondylitis (AS): Administer celecoxib 200 mg once daily, or 100 mg per dose twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg daily. If no effect is observed after 6 weeks of treatment with 400 mg daily, other treatment options should be considered. 4. Acute pain and primary dysmenorrhea: The recommended initial dose is celecoxib 400 mg, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose as needed is 200 mg per dose twice daily. ○ Patients with hepatic impairment: In patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication should be discussed with a physician or pharmacist if the patient regularly consumes a significant amount of alcohol, as it may increase the risk of gastrointestinal bleeding. This medication may increase the risk of serious cardiovascular events, myocardial infarction, or stroke, and should only be used at the lowest effective dose for the shortest duration. Serious gastrointestinal adverse reactions, such as gastrointestinal perforation, ulcers, and bleeding, may occur, particularly in elderly patients or those with a history of gastrointestinal diseases. This medication should not be administered to individuals with certain allergies, severe liver or kidney disease, cardiovascular diseases, pregnant women, or nursing mothers. Patients with impaired liver or kidney function, hypertension, asthma, heart failure, or diabetes should use this drug with particular caution and follow the physician's instructions strictly. Patients must regularly monitor blood pressure, liver function, kidney function, etc., while taking this medication, and should avoid driving or operating machinery if dizziness or drowsiness occurs. This medication may interact with several drugs, so it is essential to inform the physician or pharmacist of any other medications being taken. Women who are pregnant or planning to become pregnant should consult before using this medication, as it may affect fertility, and should not take it during pregnancy. Safety and efficacy for children and adolescents have not been established, thus it is not recommended. In case of overdose, symptoms such as nausea, vomiting, drowsiness, and gastrointestinal bleeding may occur, and immediate medical attention should be sought. This medication should be kept out of reach of children, and care should be taken not to transfer it to another container as this may negatively affect the quality.

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcers, bleeding, bronchitis, sinusitis, upper respiratory infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle tension, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental diseases, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, increased liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, vesicular dermatitis, peripheral edema, facial edema, influenza-like illness, injury, injury, dyspepsia, diarrhea, irritable bowel syndrome, increased bowel movement frequency, abdominal pain, epigastric pain, bloating, nausea, constipation, diverticulitis, dysphagia, belching, esophagitis, gastritis, gastrointestinal ulcer, gastroesophageal reflux, gastric discomfort, gastrointestinal disorders, hemorrhoids, hiatal hernia, bloody stools, dry mouth, stomatitis, lichen planus, dental diseases, vomiting, exacerbation of gastrointestinal inflammation, angular cheilitis, intestinal obstruction, intestinal perforation, gastrointestinal bleeding, hemorrhagic colitis, esophageal perforation, pancreatitis, bowel obstruction, alveolar osteitis after tooth extraction, intestinal anastomosis ulcer, melena, glossitis, aphthous stomatitis, oral mucosal blister formation, numbness of the mouth, oral pain, headache, dizziness, leg cramps, tension, sensory reduction, migraine, neuralgia, neuropathy, sensory anomalies, cerebral infarction, aseptic meningitis, ataxia, suicide, anosmia, ageusia, back pain, allergy exacerbation, allergic reactions, weakness, chest pain, fluid retention, peripheral edema, generalized edema, facial swelling, fatigue, lethargy, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactic-like reaction, angioedema, insomnia, loss of appetite, anxiety, increased appetite, depression, neural hypersensitivity, drowsiness, fatal intracranial hemorrhage, confusion, hallucinations, epilepsy exacerbation, upper respiratory infection, sinusitis, pharyngitis, rhinitis, bronchitis, bronchospasm, exacerbated bronchospasm, cough, dyspnea, laryngitis, pneumonia, nosebleed, voice disorders, vesicular dermatitis, petechiae, rash, alopecia, dermatitis, nail diseases, photosensitivity reactions, pruritus, erythematous rash, maculopapular rash, skin disorders, dry skin, increased sweating, urticaria, erythema multiforme, exfoliative dermatitis, Stevens-Johnson syndrome, toxic epidermal necrolysis, eczema, lipoma, allergic dermatitis, petechiae, dandruff, drug rash with eosinophilia and systemic symptoms, arrhythmia, ventricular hypertrophy, exacerbated hypertension, angina pectoris, unstable angina, coronary artery disorders, myocardial infarction, heart failure, palpitations, tachycardia, stroke, aortic valve insufficiency, hematoma, bradycardia, syncope, ventricular fibrillation, pulmonary embolism, cerebrovascular accident, peripheral gangrene, thrombotic vein inflammation, vasculitis, deep vein thrombosis, cerebral hemorrhage, solitary, wound infection, gingivitis, herpes simplex, herpes zoster, bacterial infection, fungal infection, soft tissue infection, viral infection, moniliasis, genital moniliasis, otitis media, breast tenderness, menopausal symptoms, fibrocystic breast disease, chest pain, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostate disorders, ovarian cysts, hearing loss, ear abnormalities, ear pain, tinnitus, deafness, liver function abnormalities, elevated ALT, elevated AST, increased γ-GTP, increased ALP, positive urobelinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, liver necrosis, increased serum sodium, increased serum potassium, elevated BUN, elevated CPK, diabetes mellitus, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, elevated NPN, increased creatinine, elevated alkaline phosphatase, weight gain, loss of appetite, elevated LDH, hypoglycemia, hyponatremia, synovial sac, arthralgia, osteoarthritis, skeletal abnormalities, myalgia, cervical tension, synovitis, tendinitis, myositis, leg cramps, fractures, tendon rupture, pain in extremities, muscle rigidity, decreased hematocrit, increased hemoglobin, petechiae, nosebleed, thrombocytopathy, anemia, thrombocytopenia, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, eczematous dermatitis, contact dermatitis, injection site reactions, skin nodules, taste disorder, albuminuria, cystitis, hematuria, dysuria, polyuria, nephrolithiasis, urinary incontinence, urinary tract infection, visual disturbances, cataracts, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, elevated β2-microglobulin, increased NAG, positive urine hemoglobin, positive urine protein, renal dysfunction, acute kidney injury, interstitial nephritis, menstrual disorders, chest pain, anaphylactic reaction, hallucinations, cerebral hemorrhage, aseptic meningitis, loss of taste, loss of smell, vasculitis, pulmonary embolism, interstitial pneumonia, gastrointestinal bleeding, hepatitis, liver failure, fulminant hepatitis, liver necrosis, cholestasis, cholestatic hepatitis, jaundice, phototoxic reactions, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized exanthematous pustulosis, exfoliative dermatitis, generalized vesicular fixed drug eruption, fixed drug eruption, acute kidney injury, hyponatremia, tubulointerstitial nephritis, nephrotic syndrome, minuscule lesional glomerulonephritis, female infertility

This medication should be stored in a tightly sealed container to prevent air exposure, preferably at room temperature between 15 to 30 degrees Celsius. Proper storage will maintain the medication's effectiveness.

Appearance

A white capsule with yellow stripes containing a white to pale yellow powder.

Package unit

30 capsules/bottle, 100 capsules/bottle