Tovastin Tablet 20mg (Atorvastatin Calcium Trihydrate)

Adult dose

For the treatment of hyperlipidemia, the recommended initial dose is 10 mg once daily. If a greater reduction in LDL cholesterol levels is required, it may be started with 20 mg or 40 mg once daily. Dosing should be in the range of 10-80 mg once daily, individualized according to treatment goals and patient response. Patients with homozygous familial hypercholesterolemia should be given 10-80 mg once daily.

Child dose

The recommended initial dose for pediatric patients (10-17 years) with heterozygous familial hypercholesterolemia is 10 mg once daily, and the maximum dose is 20 mg per day. The administration dosage is adjusted according to therapeutic goals, with adjustments made every 4 weeks as needed.

This medication may pose a risk of muscle problems; therefore, if muscle pain, weakness, or significantly elevated creatine kinase levels occur, use should be discontinued immediately. Patients with active liver disease or severely impaired liver function, those with muscle diseases, pregnant women or women who may become pregnant, children under 10 years old, and those taking specific antiviral treatments should not take this medication. Caution is advised for individuals with a history of alcohol dependence or liver disease, those with impaired kidney function, hypothyroid patients, those with a past of muscle disorders, and elderly patients. This medication is generally well tolerated but can occasionally cause various side effects such as liver function abnormalities, muscle pain, indigestion, headache, allergic reactions, and skin rashes. If symptoms occur, consult a doctor. If muscle pain is accompanied by fatigue or fever, contact a doctor immediately and undergo testing, as discontinuation may be necessary in severe cases. As this medication is metabolized in the liver, patients with poor liver function may require dosage adjustments and should stop use if symptoms of hepatitis (nausea, vomiting, malaise, etc.) appear. Appropriate contraception must be practiced during treatment. Pregnant or breastfeeding women should not use this medication. This medication may interact with several drugs, thus it is crucial to inform your doctor or pharmacist of any other medications being taken, especially when co-administered with specific antibiotics, antifungals, antivirals, or immunosuppressants. In case of overdose, there are no specific antidotes; therefore, treatment should be symptomatic, and liver function and muscle condition should be monitored periodically. Keep out of reach of children, and it is safest to store it in the original container. Elderly patients and those with renal impairment are at higher risk for myopathy; hence careful observation during treatment is necessary.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, mucosal pain in the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, cough plus respiratory abnormalities with fever, jaundice (yellowing of skin or eyes), extreme lethargy, sudden and severe headaches, thunderclap headaches, seizures, confusion, vision abnormalities, paralysis, urination abnormalities

Mild side effects

• Weakness
• malaise
• chest pain
• peripheral edema
• fatigue
• fever
• rhinitis
• hyperglycemia
• hypoglycemia
• weight gain

This medication may be sensitive to air or humidity; therefore, it should be stored in a tightly sealed container. Optimal storage temperature should be maintained at room temperature between 1 and 30 degrees Celsius. This ensures the drug's effectiveness is preserved.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle