Simastan (Losartan Potassium)

Adult dosage

Hypertension: The initial and maintenance dose is 50mg once daily, regardless of meals. If needed, the dose may be increased to 100mg once daily. Elderly patients: In elderly patients under 75 years of age, initial dosing adjustment is not necessary. For those over 75 years of age, an initial dose of 25mg once daily is recommended. Patients with renal impairment: Adjustments in initial dosing are not necessary for patients with mild renal impairment.

Children's dosage

Children and adolescents aged 6 years and older: For those weighing between 20kg and less than 50kg, the initial dose is 25mg once daily, and the maximum may be increased to 50mg once daily depending on blood pressure response.

This medication can cause serious harm to the fetus if taken during pregnancy, especially in the second and third trimesters, so it should not be taken by pregnant women or women who may become pregnant. If pregnancy is confirmed, the medication should be discontinued immediately, and regular examinations to check the health of the fetus are necessary. This medication should not be administered to patients with severely impaired liver function, certain hereditary diseases, or specific kidney diseases. Caution is required in elderly patients, patients with hyperkalemia, and patients with mild to moderate liver dysfunction, as blood pressure may drop too low. As this medication lowers blood pressure, dizziness or fainting may occur while taking it, so caution is necessary when driving or operating machinery. It is safe not to take this medication with potassium supplements or medications containing potassium, as it can elevate potassium levels. Regular checks of blood pressure, kidney function, electrolyte levels, etc., should be done during use to confirm any abnormalities. Rarely, side effects such as liver dysfunction, blood abnormalities, muscle pain, and skin rashes may occur, so if any unusual symptoms appear, contact a doctor immediately. This medication is not recommended for breastfeeding women, and if it needs to be taken, it is advisable to stop breastfeeding. In case of overdose, hypotension and cardiac arrhythmias may occur, so appropriate treatment should be sought immediately at a medical facility.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, angioedema (which may cause airway obstruction due to laryngeal/glottic swelling or swelling of the face/lips/pharynx/tongue), severe allergic reactions, severe rash with high fever, blisters, skin peeling, pain in the oral/ocular mucosa, severe skin adverse reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory problems accompanied by cough and fever,

Mild side effects

• Muscle cramps
• back pain
• leg pain
• dizziness
• congestion
• upper respiratory infection
• sinusitis
• nausea
• diarrhea
• dyspepsia

This medication should be stored in a tightly closed container to prevent air or moisture from entering. It is important to maintain a storage temperature between 1 degree and 30 degrees Celsius.

Appearance

White oval film-coated tablets

Package unit

30 tablets/bottle, 300 tablets/bottle