Amidm M Tablet 2/500 mg

Adult dosage

This drug is administered 1-2 times a day before meals or with meals. The dosage can be adjusted based on the patient's current therapy regimen, efficacy, and tolerance, with appropriate blood sugar monitoring needed. It is generally recommended to start treatment at a low dose and adjust according to blood glucose levels. In clinical trials, the initial dose per day was glymepiride/metformin hydrochloride 2mg/500mg, gradually increased to 8mg/20.

This drug may cause severe lactic acidosis or hypoglycemia; therefore, administration should be temporarily stopped and a doctor consulted if there is a sudden decline in kidney function or symptoms of dehydration. It should not be administered to patients with decreased kidney function or severe liver dysfunction, pregnant or breastfeeding women, and patients who will undergo specific tests or surgery. Given the risk of hypoglycemia, special caution is required when nutritional status is poor, meals are skipped, strenuous exercise is undertaken, or excessive alcohol is consumed. Gastrointestinal symptoms such as diarrhea, nausea, and vomiting may occur initially, but they are usually temporary and can be reduced by taking the medication with food. If allergic reactions or severe skin rashes, difficulty breathing, or other symptoms occur, seek immediate medical attention, and regular blood tests should be conducted to check for anemia or liver dysfunction. This medicine may interact with other drugs; therefore, it is essential to inform your doctor or pharmacist of any other medications being taken. Pregnant women or those planning pregnancy are recommended to switch to insulin therapy instead of using this medication. Children and the elderly require careful assessment and ongoing monitoring before use. In cases of overdose, hypoglycemic symptoms may appear, so contact a medical facility immediately, and emergency measures such as administering glucose should be initiated if necessary. Caution is necessary when driving or operating machinery due to the risk of accidents from hypoglycemia or dizziness. This medication should be stored out of reach of children and should not be transferred to other containers.

Serious side effects

• Urticaria
• severe swelling (edema)
• difficulty breathing
• chest tightness
• severe allergic reactions
• severe skin reactions
• yellowing of the skin or eyes (jaundice)
• liver abnormalities
• severe rash with fever
• blisters

Mild side effects

Nausea, vomiting, abdominal bloating, loss of appetite, dyspepsia, constipation, abdominal pain, metallic taste, visual impairment, erythema, itching, rash, urticaria, feelings of fullness or pressure in the upper abdomen, diarrhea, thrombocytopenia, leukopenia, hemolytic anemia, anemia, agranulocytosis, pancytopenia, vitamin B12 decrease, increased liver enzymes, liver function impairment, hepatitis, allergic vasculitis, photo sensitivity of skin, serum sodium changes.

This medication should be stored in a tightly sealed container to prevent air exposure. The storage temperature should ideally be maintained between 1 and 30 degrees Celsius.

Appearance

White, oblong film-coated tablet

Package unit

100 tablets/bottle, 30 tablets/PTP (10 tablets/PTP × 3)