Rhinase Enteric-Coated Tablets (Aspirin)

Adult dose

Enteric-coated tablets: Take 1 tablet once daily before meals with sufficient water. Enteric-coated capsules: Take 1 capsule once daily before meals with sufficient water.

This medication may cause gastrointestinal bleeding in individuals who regularly consume more than three drinks of alcohol daily; thus, it should be discussed with a doctor or pharmacist. This medication should not be administered to certain patients, including those allergic to salicylate drugs, those with peptic ulcers, those with a history of aspirin-induced asthma, patients with hemophilia, those with severe liver or kidney dysfunction, patients with severe heart failure, patients with a tendency to bleed, those taking high doses of methotrexate, and pregnant women in the third trimester. Patients with kidney or liver dysfunction, cardiovascular diseases, blood disorders, bronchial asthma, those scheduled for surgery, children under three years, patients with a history of allergies, the elderly, patients taking anticoagulants, and those with glucose-6-phosphate dehydrogenase deficiency should use this medication cautiously. During medication, allergic reactions, skin rash, gastrointestinal bleeding, abnormalities in kidney or liver function, blood disorders, and neurological symptoms may occur. If any unusual symptoms arise, one should immediately stop taking the medication and consult a doctor. This medication should be used cautiously in children under 14 with chickenpox or influenza, with close monitoring of the patient's condition afterwards. This medication helps alleviate symptoms but does not treat underlying causes, so appropriate clinical evaluations and other treatments should also be considered for chronic or acute conditions. Some symptoms like body temperature drop, exhaustion, and cold extremities may occur after taking the medication, requiring careful monitoring of particularly children, the elderly, and patients with debilitating illnesses. When treating inflammation caused by infection, this medication should be used carefully alongside appropriate antibiotics, with the elderly and children receiving the minimum effective dose while being monitored for adverse reactions. Taking this medication within one week before surgery may increase the risk of bleeding, so it's essential to consult a doctor in such cases. Overdosing on this medication can lead to signs of toxicity, which may be life-threatening in severe cases, so caution is advised. This medication increases the risk of bleeding due to its platelet aggregation inhibition effect, so patients with a tendency to bleed should exercise particular caution when taking it. Patients with gout should be aware that this medication can reduce uric acid excretion, potentially triggering gout attacks. Taking this medication along with other non-steroidal anti-inflammatory drugs may reduce its effectiveness or increase the risk of side effects, so consulting a physician is essential. If symptoms such as rash, fever, or lymph node swelling occur while taking this medication, one should stop taking it immediately and seek a doctor's evaluation. There is a high potential for interactions with other drugs, so when taken with anticoagulants, hypoglycemic agents, lithium preparations, methotrexate, etc., consulting a doctor or pharmacist is imperative. In the first and second trimesters of pregnancy, it should only be taken at the lowest effective dose when necessary; during the third trimester, it should not be taken as it poses risks to both the fetus and the mother. This medication is excreted in breast milk, so it is best to avoid taking it while breastfeeding. Elderly patients are at a higher risk of side effects, so starting with a low dose and observing their condition carefully is advised. Care should be taken to prevent damaging the enteric coating and it should not be taken with alkalizing agents. Store this medication out of reach of children and keep it in its original container to maintain the quality of the product.

Serious side effects

• Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor (severe allergic reaction)
• Difficulty breathing, asthma attacks (respiratory issues)
• Kidney impairment and acute renal failure (severe swelling or urinary abnormalities)
• Possible hepatic impairment (jaundice)
• Severe gastrointestinal bleeding, peptic ulcer and perforation
• Reye's syndrome, Stevens-Johnson syndrome, DRESS syndrome (severe skin reactions)
• Aplastic anemia, impaired platelet function resulting in

Mild side effects

• Hypersensitivity: Erythema, itching, nasal congestion, rash, swelling, symptoms of rhinitis, conjunctivitis
• Skin reactions: Rarely, Reye's syndrome, drug reactions with eosinophilia and systemic symptoms (DRESS syndrome), Stevens-Johnson syndrome, exfoliative dermatitis
• Blood disorders: Aplastic anemia, anemia, leukopenia, thrombocytopenia, impaired platelet function
• Gastrointestinal effects: Loss of appetite, heartburn, stomach pain, nausea, vomiting
• Neurological effects: Ear

Drug interactions

This medication may increase the risk of bleeding or decrease kidney function when used in conjunction with other non-steroidal anti-inflammatory drugs and salicylate preparations. It may also interact with anticoagulants, ibuprofen, naproxen, some non-steroidal anti-inflammatory drugs, thrombolytics, other platelet aggregation inhibitors, hemostatics, diabetes treatment drugs (insulin preparations, tolbutamide, etc.), uricosurics (benzbromarone, probenecid), thiazide diuretics, lithium preparations,

This medication is susceptible to air and moisture, so it should be stored in a tightly sealed container. Additionally, to maintain the medication's efficacy, it is advisable to store it at room temperature below 25 degrees Celsius.

Appearance

White, round enteric-coated film-coated tablets

Package unit

30 tablets/bottle, 500 tablets/bottle