Olmesartan Medoxomil 10 mg Tablets

Adult dose

The recommended initial dose is 10 mg once daily, and it can be taken regardless of meals. If blood pressure is not adequately controlled, it may be increased to 20 mg once daily. If additional blood pressure-lowering effect is needed, it may be increased up to a maximum of 40 mg once daily. The blood pressure-lowering effect typically appears within 2 weeks of starting treatment, with maximum effect observed around 8 weeks. It is recommended to take the medication at the same time each day (e.g., in the morning) whenever possible.

Child dose

The safety and efficacy in children have not been established.

This medication can cause serious harm or death to the fetus and newborn if administered to pregnant women in the second and third trimesters, so it must be discontinued immediately upon confirmation of pregnancy. This medication should not be used in certain patients. For example, individuals allergic to this medication or its components, pregnant or breastfeeding women, patients on kidney dialysis, those with severe liver impairment, biliary obstruction, lactose intolerance or related genetic disorders, certain diabetic patients, and patients with severely reduced kidney function should not take this medication. Hypotension can occur in patients with reduced blood volume or body salts, so the pre-treatment status should be thoroughly checked, and careful monitoring should continue during treatment. This medication may affect kidney function, so patients with weakened kidney function or transplant recipients should frequently check their kidney status through blood tests, and its use is not recommended in cases of severe kidney impairment. Patients with renal artery stenosis, at risk of hyperkalemia, or those with aortic or cardiac valve disease require special caution when taking this medication. During treatment, blood pressure can drop and cause dizziness, so it is advisable to avoid driving or operating hazardous machinery. The blood pressure-lowering effect of this medication may vary among different ethnic groups, and it may be less effective in Black patients. The side effects of this medication are generally mild and temporary, with dizziness being the most common. Other potential side effects include abdominal pain, headache, muscle pain, rash, and hyperkalemia. Taking this medication during pregnancy may lead to decreased kidney function in the fetus, resulting in reduced amniotic fluid volume and various malformations or developmental disorders; thus, it should not be taken during pregnancy. Breastfeeding women should exercise caution, as this medication may pass into breast milk, potentially causing adverse reactions in the baby, and breastfeeding should be interrupted or medication stopped if necessary. Safety and efficacy in children have not been sufficiently established, so it should be administered cautiously in this population. In elderly patients, the medication may remain in the body for a longer period, requiring dosage adjustments and careful monitoring. In case of overdose, blood pressure decrease and heart rhythm abnormalities may occur, requiring immediate treatment and supportive therapy if necessary. This medication may interact with other drugs, so caution is necessary, especially when taken with potassium-sparing diuretics, lithium, or non-steroidal anti-inflammatory drugs. Rare gastrointestinal disorders similar to chronic malabsorption syndrome have been reported, so if severe diarrhea or weight loss occurs during long-term use, consult a doctor. If any abnormal symptoms occur during treatment, immediate consultation with medical personnel is necessary for appropriate measures.

Serious side effects

Hives, severe swelling (including angioedema, facial swelling, peripheral edema), chest pain, difficulty breathing (including asthma), cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in oral/conjunctival mucosa, jaundice of skin or eyes, severe liver dysfunction, sudden severe headache, seizures, confusion, vision changes, paralysis, significant decrease in urine output, elevated blood pressure, acute kidney failure, elevated serum creatinine

Mild side effects

• Dizziness
• headache
• palpitations
• hypercholesterolemia
• hyperlipidemia
• hyperuricemia
• joint pain
• arthritis
• muscle pain
• abdominal pain

This medication should be stored in a tightly closed container to avoid exposure to air and moisture. It is important to maintain the storage temperature between 1 and 25 degrees Celsius.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle