Medication info
Abacue Tablet 10 mg (Atorvastatin Calcium Hydrate)

Abacue Tablet 10 mg (Atorvastatin Calcium Hydrate)

Prescription medicationTablet경구
Ingredient · strength
Atorvastatin Calcium Hydrate›10.85mg / 1 tablet
Manufacturer / importer
조아제약(주)
Appearance
White circular film-coated tablet
Packaging
30 T/bottle, 100 T/bottle
Approval status
Active

MFDS item code 201306873 · Approved 2013.04.11 · Insurance code 644602690

Summary

Main use
Reduction of the risk of myocardial infarction and stroke, improvement of hypercholesterolemia
Who takes it
Adults · Children
Adult dose
The recommended initial dose of atorvastatin is 10 mg once daily, and for those requiring greater LDL-cholesterol reduction, treatment may start at 20 mg or 40 mg once daily. This drug is administered at a dosage range of 10 to 80 mg once daily. Lipid levels should be analyzed and dosages adjusted within 2 to 4 weeks after starting and/or adjusting the dose.
Child dose
The recommended initial dose for pediatric patients (ages 10 to 17) with heterozygous familial hypercholesterolemia is 10 mg once daily, with a maximum dose of 20 mg once daily. Dosage should be adjusted at intervals of 4 weeks or more.

Ingredients

Manufacturer
조아제약(주)

Efficacy & effects

Reduction of the risk of myocardial infarction and stroke, improvement of hypercholesterolemia

  • Coronary heart disease
  • myocardial infarction
  • stroke
  • chronic stable angina
  • retinopathy
  • albuminuria
  • hypertension
  • congestive heart failure
  • angina
  • hypercholesterolemia
  • dyslipidemia
  • abnormal beta-lipoproteinemia
View approved original text

This medication helps lower the risk of cardiovascular diseases. It is particularly effective in reducing risks related to various cardiac and vascular conditions such as myocardial infarction, stroke, vascular surgeries, and angina. It controls cholesterol and triglyceride levels in patients with hyperlipidemia and increases HDL-cholesterol levels, complementing dietary effects. Additionally, it is used to lower total cholesterol and LDL-cholesterol levels in pediatric and adult patients with a family history or several risk factors. This drug is effectively used for the prevention of cardiovascular diseases and improvement of dyslipidemia.

How to take

Adult dose

The recommended initial dose of atorvastatin is 10 mg once daily, and for those requiring greater LDL-cholesterol reduction, treatment may start at 20 mg or 40 mg once daily. This drug is administered at a dosage range of 10 to 80 mg once daily. Lipid levels should be analyzed and dosages adjusted within 2 to 4 weeks after starting and/or adjusting the dose.

Child dose

The recommended initial dose for pediatric patients (ages 10 to 17) with heterozygous familial hypercholesterolemia is 10 mg once daily, with a maximum dose of 20 mg once daily. Dosage should be adjusted at intervals of 4 weeks or more.

Precautions

This drug may cause adverse reactions in muscles, so if symptoms such as muscle pain or weakness occur, especially with fever or malaise, inform your doctor immediately. This drug can affect liver function, so patients with liver disease or elevated liver function tests should not use it, and regular liver function tests should be conducted during treatment. Pregnant women, women who may become pregnant, and breastfeeding mothers should not take this medication, and fertile women should use appropriate contraception while taking it. This medication is not to be administered to children under 10 years of age or to patients with specific genetic lactose intolerance. The risk of muscle-related side effects may be increased in patients with kidney disease, so caution is advised in those with impaired kidney function. This drug may interact with certain antibiotics, antifungals, and antivirals, which may require dose adjustments or discontinuation when taken together. Taking this drug with grapefruit juice may increase blood concentrations, raising the risk of side effects, so grapefruit juice should be avoided. During the course of taking this medication, if you experience symptoms such as muscle pain, fatigue, or fever, consult medical personnel immediately and conduct blood tests if needed to check for muscle damage. Additionally, this drug can cause severe allergic reactions in the skin, so if rash, itching, or vesicular skin changes occur, stop using it immediately and seek medical attention. Elderly individuals or patients with impaired liver or kidney function are at higher risk of side effects from this drug and should use it with extra caution, requiring regular monitoring. In cases of overdose, there is no specific antidote, so appropriate treatment should be administered based on symptoms, along with liver function and muscle-related tests. This medication should be kept out of the reach of children and stored in its original container to prevent degradation or misuse.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pale appearance, severe rash with high fever, blisters, skin peeling, pain in the oral/mucous membranes, difficulty breathing, asthma attack, respiratory anomalies with cough and fever, yellowing of the skin or eyes (jaundice), extreme drowsiness, sudden severe headache, lightning headache, seizures, altered consciousness, visual disturbances, paralysis, urination problems.

Mild side effects

  • Fatigue
  • malaise
  • chest pain
  • peripheral edema
  • tiredness
  • fever
  • rhinitis
  • hyperglycemia
  • hypoglycemia
  • weight gain
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  • loss of appetite
  • constipation
  • abdominal distension
  • dyspepsia
  • nausea
  • diarrhea
  • abdominal pain
  • vomiting
  • belching
  • pancreatitis
  • oropharyngeal and laryngeal pain
  • nosebleeds
  • insomnia
  • nightmares
  • headache
  • dizziness
  • paresthesia
  • sensory loss
  • dysgeusia
  • memory loss
  • peripheral neuropathy
  • myalgia
  • arthralgia
  • limb pain
  • musculoskeletal pain
  • muscle cramps
  • joint pain.

Not everyone experiences these, and they can vary from person to person.

Storage

This drug should be stored in a tightly closed container to prevent exposure to air and moisture. It is recommended to maintain a storage temperature between 1 and 30 degrees Celsius.

Appearance and packaging

Appearance

White circular film-coated tablet

Package unit

30 T/bottle, 100 T/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.