Medication info
Rafuton Tablet 10mg (Rapotidine)

Rafuton Tablet 10mg (Rapotidine)

Prescription medicationTabletOral
Ingredient · strength
Lafutidine›10mg / 1 tablet
Manufacturer / importer
Genewon Science Co., Ltd.
Appearance
White circular film-coated tablet
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Active

MFDS item code 201306454 · Approved 2013.03.22 · Insurance code 671703970

Summary

Main use
Treatment of gastrointestinal disorders (such as ulcers and gastritis), preanesthetic medication, and adjunctive therapy for eradication
Who takes it
Adults
Adult dose
1. Short-term treatment of gastric ulcers: The usual dose is 10mg of lafutidine orally twice daily, in the morning and before bedtime. In clinical trials lasting up to 8 weeks, most ulcers healed within 8 weeks, although the healing period may vary from patient to patient. 2. Short-term treatment of duodenal ulcers: The usual dose is 10mg of lafutidine orally twice daily, in the morning and before bedtime. In clinical trials lasting up to 6 weeks, most ulcers healed within 6 weeks, although the healing period may vary from patient to patient. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis: The usual dose is 10mg of lafutidine orally once daily before bedtime. In clinical trials lasting up to 2 weeks, most lesions healed within 2 weeks, although the healing period may vary from patient to patient. 4. Antibiotic combination therapy for patients with peptic ulcer disease infected with Helicobacter pylori: Administer lafutidine 20mg, clarithromycin 500mg, and amoxicillin 1000mg twice daily for 7 or 14 days. 5. Premedication before anesthesia: The usual dose is 10mg of lafutidine orally twice (before bedtime on the day before surgery and 2 hours before anesthesia on the day of surgery). 6. Treatment of reflux esophagitis: Administer 10mg of lafutidine orally twice daily.

Ingredients

Manufacturer
Genewon Science Co., Ltd.

Efficacy & effects

Treatment of gastrointestinal disorders (such as ulcers and gastritis), preanesthetic medication, and adjunctive therapy for eradication

  • Gastric ulcer
  • duodenal ulcer
  • acute gastritis
  • gastric mucosal lesions from chronic gastritis
  • peptic ulcer
  • gastroesophageal reflux disease
View approved original text

This medication is used for the treatment of gastric ulcers and duodenal ulcers, helping to improve gastric mucosal damage caused by acute and chronic gastritis. It is also used in combination with antibiotics in patients with Helicobacter pylori infections to enhance treatment efficacy. It may also be safely administered prior to anesthesia and is effective for the treatment of gastroesophageal reflux disease. Overall, it is used to alleviate and treat symptoms related to various gastrointestinal diseases.

How to take

Adult dose

1. Short-term treatment of gastric ulcers: The usual dose is 10mg of lafutidine orally twice daily, in the morning and before bedtime. In clinical trials lasting up to 8 weeks, most ulcers healed within 8 weeks, although the healing period may vary from patient to patient. 2. Short-term treatment of duodenal ulcers: The usual dose is 10mg of lafutidine orally twice daily, in the morning and before bedtime. In clinical trials lasting up to 6 weeks, most ulcers healed within 6 weeks, although the healing period may vary from patient to patient. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis: The usual dose is 10mg of lafutidine orally once daily before bedtime. In clinical trials lasting up to 2 weeks, most lesions healed within 2 weeks, although the healing period may vary from patient to patient. 4. Antibiotic combination therapy for patients with peptic ulcer disease infected with Helicobacter pylori: Administer lafutidine 20mg, clarithromycin 500mg, and amoxicillin 1000mg twice daily for 7 or 14 days. 5. Premedication before anesthesia: The usual dose is 10mg of lafutidine orally twice (before bedtime on the day before surgery and 2 hours before anesthesia on the day of surgery). 6. Treatment of reflux esophagitis: Administer 10mg of lafutidine orally twice daily.

Precautions

This medication should not be used by individuals with allergies to specific ingredients. Additionally, since it contains lactose, patients with lactose intolerance or related genetic conditions should not take it. People allergic to soybean oil, soybeans, or peanuts should also avoid this medication. Extra caution is required for individuals with a history of drug allergies, patients with liver or kidney dysfunctions, those undergoing dialysis, and the elderly. In particular, patients with lipid metabolism issues or those needing to take lipid emulsions should use this drug cautiously. While taking this medication, there is a risk of severe allergic reactions such as anaphylaxis; if symptoms like facial pallor, lowered blood pressure, or difficulty breathing occur, immediate cessation of the drug and a visit to the hospital are necessary. Liver function abnormalities or jaundice symptoms may also occur, so liver function should be regularly monitored, and medication should be stopped and treated if symptoms develop. Severe side effects such as agranulocytosis or thrombocytopenia leading to decreased blood cell count can occur; symptoms like sore throat, fever, and body weakness should be reported to healthcare providers. Additionally, a variety of side effects such as skin rashes, seizures, and cardiac issues have been reported. This medication may lead to symptoms of indigestion, diarrhea, constipation, nausea, headache, dizziness, and fatigue. If any of these symptoms are severe or persistent, consult a physician. Particularly in cases where symptoms of gastric cancer or malignant tumors are suspected, tests should be performed before taking this medication, and the drug should be stopped if malignancy is confirmed. Routine blood tests, liver function, and kidney function assessments should be conducted to check for abnormalities during treatment. Elderly patients may have decreased bodily functions, so dosage and administration intervals should be adjusted and observed carefully. Dialysis patients may have elevated drug concentrations in the blood, so starting at a low dose and taking it cautiously is advisable. Pregnant women or those who may become pregnant should consult a doctor and take it only if necessary; nursing mothers should avoid this medication as it may be excreted in breast milk. Safety in pediatric patients has not been sufficiently established; thus, it is advisable not to use this medication in children. This medication should be stored out of the reach of children and kept in its original container to maintain quality and prevent misuse.

Side effects

  • Shock
  • symptoms of anaphylaxis
  • pallor
  • hypotension
  • generalized rash
  • dyspnea
  • impaired liver function
  • jaundice
  • agranulocytosis
  • pharyngitis
Show 83 more
  • general malaise
  • fever
  • thrombocytopenia
  • pancytopenia
  • aplastic anemia
  • convulsions
  • interstitial nephritis
  • Stevens-Johnson syndrome
  • Lyell syndrome
  • rhabdomyolysis
  • heart block
  • reduced contraction
  • constipation
  • diarrhea
  • hard stools
  • nausea
  • vomiting
  • abdominal distension
  • loss of appetite
  • headache
  • insomnia
  • drowsiness
  • reversible confusion
  • hallucinations
  • altered consciousness
  • dizziness
  • hypothermia
  • heat sensation
  • facial flushing
  • leukocytosis
  • eosinophilia
  • leukopenia
  • erythrocytopenia
  • decreased hematocrit
  • elevated ALT
  • elevated AST
  • elevated Al-P
  • elevated γ-GTP
  • elevated T-Bil
  • elevated LDH
  • elevated TTT
  • abnormal urinary protein
  • elevated BUN
  • elevated serum uric acid
  • elevated Cl
  • prolonged half-life
  • elevated Na
  • decreased K
  • gynecomastia
  • edema
  • malaise
  • glossitis
  • headache
  • chest pain
  • subdural hematoma
  • urticaria
  • skin rash
  • abdominal pain
  • dyspepsia
  • enteritis
  • gastric ulcer
  • erosive gastritis
  • duodenitis
  • distension
  • rhinitis
  • upper respiratory infection
  • bronchopneumonia
  • tinea
  • carotid stenosis
  • cough
  • oropharyngeal pain
  • oropharyngeal discomfort
  • wet cough
  • fatigue
  • chest pain
  • limb pain
  • arthralgia
  • cervical pain
  • pruritus
  • acne
  • contusion
  • insomnia
  • nonalcoholic fatty liver hepatitis

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture, ideally at room temperature between 1 and 30 degrees Celsius. Proper storage ensures the efficacy of the drug is maintained and prevents degradation.

Appearance and packaging

Appearance

White circular film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.