Medication info
Loxrofen Tablets (Loxoprofen Sodium Hydrate)

Loxrofen Tablets (Loxoprofen Sodium Hydrate)

Prescription medicationTablet경구
Ingredient · strength
Loxoprofen Sodium Hydrate›68.1mg / 1 tablet
Manufacturer / importer
(주)일화
Appearance
White to pale yellow round tablets
Packaging
30 tablets, 300 tablets / bottle
Approval status
Active

MFDS item code 201306407 · Approved 2013.03.22 · Insurance code 640902440

Summary

Main use
Anti-inflammatory and analgesic effects for chronic rheumatoid arthritis and osteoarthritis, as well as antipyretic and analgesic effects for acute upper respiratory infections.
Who takes it
Adults
Adult dose
1. For indications and effects 1, 2: Adults: Administer 60 mg of loxoprofen sodium (anhydrous) orally three times a day. For a one-time treatment, administer 60–120 mg orally. 2. For indications and effects 3: Adults: Administer 60 mg of loxoprofen sodium (anhydrous) orally. In principle, it can be taken twice a day, for a maximum of 180 mg per day. It is advisable to avoid taking it on an empty stomach.

Ingredients

Manufacturer
(주)일화

Efficacy & effects

Anti-inflammatory and analgesic effects for chronic rheumatoid arthritis and osteoarthritis, as well as antipyretic and analgesic effects for acute upper respiratory infections.

  • Chronic rheumatoid arthritis
  • osteoarthritis
  • low back pain
  • pericapsulitis of the shoulder
  • shoulder girdle syndrome
  • post-operative pain
  • post-traumatic pain
  • pain after tooth extraction
  • acute upper respiratory infections
  • acute bronchitis
View approved original text

This medication helps alleviate pain and inflammation caused by various inflammatory conditions such as chronic rheumatoid arthritis, osteoarthritis, low back pain, pericapsulitis of the shoulder, and the shoulder girdle syndrome. It is also used to relieve inflammation and pain after surgery, trauma, and tooth extraction. In addition, it has the effect of reducing fever and relieving pain in acute infectious diseases like acute upper respiratory infections. It effectively acts on various types of inflammation, pain, and fever, improving symptoms in patients.

How to take

Adult dose

1. For indications and effects 1, 2: Adults: Administer 60 mg of loxoprofen sodium (anhydrous) orally three times a day. For a one-time treatment, administer 60–120 mg orally. 2. For indications and effects 3: Adults: Administer 60 mg of loxoprofen sodium (anhydrous) orally. In principle, it can be taken twice a day, for a maximum of 180 mg per day. It is advisable to avoid taking it on an empty stomach.

Precautions

People who regularly consume more than three glasses of alcohol a day should consult a doctor or pharmacist before taking this medication, as it may cause gastrointestinal bleeding. This medication may increase the risk of cardiovascular disease; therefore, individuals with a history of heart disease or stroke or those with risk factors should exercise particular caution. If any cardiovascular symptoms occur during use, see a doctor immediately. This medication can cause serious gastrointestinal issues such as gastrointestinal bleeding, ulcers, or perforations; therefore, elderly patients or those with a history of gastrointestinal diseases should use it with caution. If gastrointestinal symptoms such as abdominal pain, bloody stools, or vomiting occur, stop taking the medication immediately and consult a physician. Patients with peptic ulcers, severe blood disorders, liver dysfunction, kidney dysfunction, heart failure, certain allergies, pregnant women in late pregnancy, and nursing mothers should not take this medication. Those with a history of peptic ulcers, hypertension, kidney disease, liver disease, asthma, or elderly patients should be particularly cautious when taking this medication and should regularly undergo check-ups as directed by their healthcare provider. This medication may cause allergic reactions such as skin rash, hives, shortness of breath, and low blood pressure; if such symptoms arise, stop taking it immediately and inform medical personnel. Various side effects can occur, including abdominal pain, vomiting, diarrhea, dizziness, headache, anemia, liver dysfunction, and kidney dysfunction; consult a physician if symptoms are severe or persistent. If taking this medication for an extended period, regular blood tests, liver function tests, and kidney function tests should be performed; if abnormalities are found, discontinue or adjust the dosage. Taking this medication in conjunction with other non-steroidal anti-inflammatory drugs increases the risk of side effects; therefore, it should not be combined, and potential interactions with certain blood pressure medications, anticoagulants, and antibiotics should be reported to your healthcare provider. In early or mid-pregnancy, it should only be taken at the minimum effective dose when necessary, and it should not be taken in late pregnancy nor while nursing. In children, safety has not been established, making it advisable not to use this medication, and elderly patients are at a higher risk of side effects, requiring special caution when using it. This medication should be kept out of reach of children and should not be stored in a different container, as this may alter its quality.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, shock, anaphylactic reaction, severe allergic reaction, peptic ulcer, perforation, hematemesis, melena, bloody stool, bleeding, shock, Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell syndrome), erythema multiforme, acute generalized exanthematous pustulosis, liver dysfunction (including jaundice), fulminant hepatitis, acute kidney failure, nephrotic syndrome, kidney damage

Mild side effects

  • Rash
  • itching
  • fever
  • abdominal pain
  • discomfort in the upper abdomen
  • loss of appetite
  • nausea
  • vomiting
  • diarrhea
  • constipation
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  • chest tightness
  • indigestion
  • stomatitis
  • dryness of the mouth
  • abdominal distension
  • drowsiness
  • numbness
  • dizziness
  • headache
  • anemia
  • hemolytic anemia
  • leukopenia
  • thrombocytopenia
  • eosinophilia
  • swelling
  • chest pain
  • anxiety
  • fatigue
  • palpitations
  • hematuria
  • proteinuria
  • fever
  • desolation
  • abnormal chest X-ray results
  • eosinophilia
  • nausea
  • vomiting
  • abdominal pain

Not everyone experiences these, and they can vary from person to person.

Storage

This medication must be stored in a tightly sealed container to protect it from air and moisture. It is advisable to maintain the storage temperature between 1 degree and 30 degrees Celsius. This helps preserve the medication's effectiveness and safety for a longer period.

Appearance and packaging

Appearance

White to pale yellow round tablets

Package unit

30 tablets, 300 tablets / bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.