Wiranthon Capsule (Lansoprazole Granules)

Adult dose

This medicine should be administered before meals. For patients who have difficulty swallowing the medicine, open the capsule, mix this medicine with a small amount (60 mL) of orange juice or tomato juice, and administer immediately. Rinse the glass with twice or more the volume of juice and drink immediately to ensure that the entire dose is taken. Do not chew or crush this medicine after opening the capsule. Short-term treatment of active duodenal ulcers: Administer lansoprazole 15 mg orally once daily for 4 weeks. Short-term treatment of active benign gastric ulcers: Administer lansoprazole 30 mg orally once daily for 8 weeks. Eradication of Helicobacter pylori to prevent recurrence of duodenal ulcers: Administer lansoprazole 30 mg with clarithromycin 250 ∼ 500 mg and amoxicillin 1,000 mg twice daily (every 12 hours) for 7 days. Treatment may be continued for up to 14 days if necessary. Eradication of Helicobacter pylori to prevent recurrence of duodenal ulcers: Administer lansoprazole 30 mg in combination with amoxicillin 1,000 mg 3 times daily (every 8 hours) for 14 days. Maintenance treatment after treatment of duodenal ulcers: Administer lansoprazole 15 mg orally once daily. Comparative clinical trials did not exceed 12 months. Treatment of nonsteroidal anti-inflammatory drug-induced gastric ulcers: Administer lansoprazole 30 mg orally once daily for 8 weeks. Comparative clinical trials did not exceed 8 weeks. Reduction of the risk of nonsteroidal anti-inflammatory drug-induced gastric ulcers: Administer lansoprazole 15 mg orally once daily for 12 weeks. Comparative clinical trials did not exceed 12 weeks. Short-term treatment of symptoms associated with gastroesophageal reflux disease: Administer lansoprazole 15 mg orally once daily for 8 weeks Short-term treatment of erosive reflux esophagitis: Administer lansoprazole 30 mg orally once daily for 8 weeks. Maintenance treatment after treatment of erosive reflux esophagitis: Administer lansoprazole 15 mg orally once daily. Pathological hypersecretory conditions, including Zollinger-Ellison syndrome: Lansoprazole dosing for pathological hypersecretory conditions varies for each patient. Treatment in adults is usually initiated at 60 mg once daily. The dose should be adjusted according to the patient's needs and may be continued as long as it is clinically effective. Doses of 90 mg per dose up to twice daily have been administered. If the daily dose exceeds 120 mg, it should be administered in divided doses. Since clearance of this medicine is reduced in elderly patients, dose adjustment is required. Do not exceed a daily dose of 30 mg. Since metabolism and excretion of this medicine may be delayed in patients with hepatic impairment, administer with caution, including dose adjustment.

Child dose

Children and adolescents 12 ∼ 17 years, short-term treatment of symptoms associated with non-erosive gastroesophageal reflux disease: 15 mg once daily for 8 weeks Children and adolescents 12 ∼ 17 years, short-term treatment of erosive reflux esophagitis: 30 mg once daily for 8 weeks Children 1 ∼ 11 years, 30 kg or less: 15 mg once daily for 12 weeks Children 1 ∼ 11 years, over 30 kg: 30 mg once daily for 12 weeks

This medication should not be used in certain patients. Patients with known allergies or a history of hypersensitivity to this medication, its components, or benzimidazole derivatives may experience severe allergic reactions if they take this medication. Patients with hypersensitivity to penicillin antibiotics or macrolide antibiotics should also avoid this medication. Additionally, patients taking certain specific medications, such as terfenadine, cisapride, pimodipine, astemizole, HIV protease inhibitors, or medications containing rilpivirine, should not use this medication concurrently. Pregnant women, as well as patients with genetic issues such as lactose intolerance, lactase deficiency, glucose-galactose malabsorption, should not take this medication. This medication should be used cautiously in people with a history of drug hypersensitivity, patients with impaired liver function, the elderly, nursing mothers, and children. Severe allergic reactions, blood abnormalities, liver dysfunction, serious skin reactions, pneumonia, nephritis, and other significant adverse effects may occur during the use of this medication. If any symptoms occur, consult a doctor immediately. Regular check-ups are necessary when taking this medication for long periods, and it should be used cautiously if malignancies like gastric cancer are suspected. This medication suppresses gastric acid secretion, which may affect the absorption of other drugs, hence consultation with healthcare professionals regarding co-administered medications is necessary. It is not safe to use this medication during pregnancy or lactation, and if it must be used, breastfeeding should be stopped. Experience with the use in pediatric patients is limited, and special caution is required when administering it to children. Elderly patients may have reduced physical function, so administration should start at lower doses and be done cautiously. In case of overdose, blood dialysis will not remove the drug, so gastric lavage or symptomatic treatment may be required. This medication should be kept out of the reach of children and should not be transferred to other containers. Due to the potential for dizziness, drowsiness, visual disturbances, etc., caution should be exercised when driving or operating machinery while taking this medication.

Anaphylaxis, anaphylactic shock, angioedema, bronchospasm, acute interstitial nephritis, urticaria, generalized rash, facial edema, dyspnea, shock, pancytopenia, agranulocytosis, hemolytic anemia, granulocytopenia, thrombocytopenia, anemia, jaundice, increased AST, increased ALT, toxic liver dysfunction, toxic epidermal necrolysis, Stevens-Johnson syndrome, DRESS syndrome, interstitial pneumonia, interstitial nephritis, acute renal failure, membranous colitis, abdominal pain, diarrhea, headache, abdominal enlargement, allergic reaction, back pain, weakness, candidiasis, carcinoma, chills, chest pain, edema, fever, flu-like symptoms, halitosis, infection, fatigue, neck stiffness, pelvic pain, angina, arrhythmia, bradycardia, tachycardia, cerebrovascular accident, cerebral infarction, hypertension, hypotension, migraine, myocardial infarction, palpitations, vasodilation, syncope, asthma, bronchitis, increased cough, epistaxis, hemoptysis, hiccups, pneumonia, upper respiratory infection, laryngeal tumor, pulmonary fibrosis, pharyngitis, pleural disorder, respiratory disorder, rhinitis, sinusitis, wheezing, acne, hair loss, pruritus, rash, contact dermatitis, skin dryness, nail disease, skin cancer, skin disease, sweating, abnormal vision, amblyopia, blepharitis, cataract, conjunctivitis, dry eyes, ear disorders, eye disorders, glaucoma, olfactory dysfunction, photophobia, retinal degeneration, taste loss, blurred vision, deafness, eye pain, otitis media, taste disturbance, tinnitus, peripheral vision loss, urinary dysfunction, renal pain, penile disorders, testicular disorders, urethral pain, polyuria, frequent urination, urinary retention, menstrual irregularities, chest tenderness, chest expansion, gynecomastia, diabetes, hematuria, erectile dysfunction, kidney stones, abdominal pain, diarrhea, taste disturbance, abdominal bloating, nausea, vomiting, stomatitis, glossitis, thirst, heartburn, gastroesophageal reflux, loss of appetite, increased AST, increased ALT, increased ALP, increased LDH, increased γ-GTP, elevated bilirubin, neutropenia, eosinophilia, leukocytosis, thrombocytopenia, rash, itching, headache, drowsiness, dizziness, insomnia, paralysis, depressive state, increased triglycerides, elevated uric acid, increased total cholesterol, decreased total cholesterol, positive urine protein, positive urine sugar, fatigue, hepatotoxicity, pancreatitis, taste disturbance, aplastic anemia, thrombotic thrombocytopenic purpura, hypomagnesemia, Clostridium difficile-associated diarrhea, fracture, myositis, erythema multiforme, acute generalized pustular psoriasis, speech impairment, urinary retention, increased AST, increased ALT, increased ALP, increased LDH, increased γ-GTP, weakness, hyponatremia, tongue paralysis, lip paralysis, limb paralysis, constipation, dizziness, migraine, dyspnea, vomiting symptoms, vertigo

This medication may be sensitive to air or moisture, so it must be stored in an airtight container. It is important to maintain a storage temperature between 1 and 30 degrees Celsius at room temperature to preserve the drug's effectiveness.

Appearance

A white to light brown granules-filled hard capsule with a white upper and lower shell.

Package unit

28 capsules/bottle, 30 capsules/bottle, 90 capsules/bottle