Hyaluronic Acid Sodium Injection

Adult administration

Typically, for adults, administer 1 vial once a week for 3 weeks either into the knee joint or the shoulder joint (shoulder joint cavity, subacromial bursa, or bicipital tendon sheath), but the frequency may be adjusted as needed based on symptoms.

This medicine should not be used in patients who have had an allergic reaction to any of its components. It should be used with caution in patients who have had allergic reactions to other medications or in patients with liver dysfunction or a history of liver disease. Additionally, caution is needed if there is a skin disease or infection at the injection site. When using this medication, severe allergic reactions such as anaphylactic shock may occur, so if symptoms appear, the injection should be stopped immediately and appropriate treatment should be received. Other allergic symptoms such as facial or periorbital swelling, rash, and itching may also occur, so if these symptoms are present, use should be stopped. Temporary pain, swelling, redness, warmth, and severe tenderness may occur at the injection site, and symptoms like nausea, vomiting, and fever may also occur. For severe arthritis, it may be advisable to use this medication after the inflammation subsides. It is preferable to take measures to stabilize the joint area after administration. If the medication leaks outside the joint cavity, it may cause pain, so it must be injected precisely into the joint cavity. Strict aseptic conditions should be maintained during injection, and if symptoms do not improve, the medication should be discontinued after three injections. If there is fluid in the joint, it is advisable to remove the fluid through aspiration before administration if needed. This medication should not be used for intravenous injection or ophthalmic use, and a 22-23 gauge needle is appropriate. Also, caution should be taken as the drug may precipitate when used with sterilizing agents such as benzalkonium chloride or chlorhexidine. The safety of this medication has not been established in pregnant women or those who may become pregnant, and it should only be used with caution when the benefits outweigh the risks. Breastfeeding women should avoid breastfeeding while using this medication as it may be transmitted through breast milk. The safety in pediatric patients has not been confirmed, so it should only be used with caution when absolutely necessary. Elderly patients may have decreased bodily functions, so special caution is required when using it.

Serious side effects

• Urticaria
• swelling (facial, eyelid, etc.)
• symptoms of shock

Mild side effects

• Hypersensitivity
• facial flushing
• itching
• pain
• swelling
• redness
• warmth
• severe local tenderness
• nausea
• vomiting

This medication should be stored in a sealed container to protect it from air and light, and should be kept away from direct sunlight. It is important to maintain a storage temperature between 1 degree and 30 degrees Celsius.

Appearance

A colorless, transparent, and viscous liquid contained in a glass vial or plastic tube (part of a prefilled syringe system) sealed with rubber stoppers on both ends.

Package unit

2ml/vial X 3